![N-[2-chloro-5-(trifluoromethyl)phenyl]-4-(piperidine-1-sulfonyl)benzamide structure](/static/products/3922/392289-88-2.webp)
N-[2-chloro-5-(trifluoromethyl)phenyl]-4-(piperidine-1-sulfonyl)benzamide
TL;DR: N-[2-chloro-5-(trifluoromethyl)phenyl]-4-(piperidine-1-sulfonyl)benzamide (CAS 392289-88-2) is a chemical compound with molecular formula C19H18ClF3N2O3S and molecular weight 446.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[2-chloro-5-(trifluoromethyl)phenyl]-4-piperidin-1-ylsulfonylbenzamide
Also Known As: N-[2-chloro-5-(trifluoromethyl)phenyl]-4-(piperidine-1-sulfonyl)benzamide, F0412-0055, N-(2-chloro-5-(trifluoromethyl)phenyl)-4-(piperidin-1-ylsulfonyl)benzamide, N-[2-chloro-5-(trifluoromethyl)phenyl]-4-piperidin-1-ylsulfonylbenzamide, N-[2-chloro-5-(trifluoromethyl)phenyl]-4-(1-piperidylsulfonyl)benzamide
| Molecular Formula | C19H18ClF3N2O3S |
|---|---|
| Molecular Weight | 446.07 g/mol |
| LogP | 4.7857 |
| Topological Polar Surface Area | 66.48 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 446.06787 |
| Heavy Atoms | 29 |
| Complexity | 1002.3497 |
Chemical Identifiers
| CAS Number | 392289-88-2 |
|---|---|
| SMILES | C1CCN(CC1)S(=O)(=O)C2=CC=C(C=C2)C(=O)NC3=C(C=CC(=C3)C(F)(F)F)Cl |
Product Overview
N-[2-chloro-5-(trifluoromethyl)phenyl]-4-(piperidine-1-sulfonyl)benzamide (CAS 392289-88-2), with molecular formula C19H18ClF3N2O3S and molecular weight 446.07 g/mol. IUPAC: N-[2-chloro-5-(trifluoromethyl)phenyl]-4-piperidin-1-ylsulfonylbenzamide.
Chemical Property Profile of N-[2-chloro-5-(trifluoromethyl)phenyl]-4-(piperidine-1-sulfonyl)benzamide
Property Insights of N-[2-chloro-5-(trifluoromethyl)phenyl]-4-(piperidine-1-sulfonyl)benzamide
The XLogP value of 4.7857 indicates that N-[2-chloro-5-(trifluoromethyl)phenyl]-4-(piperidine-1-sulfonyl)benzamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 66.48 Ų falls within the moderate polarity range, balancing permeability and solubility for N-[2-chloro-5-(trifluoromethyl)phenyl]-4-(piperidine-1-sulfonyl)benzamide. Following Lipinski's Rule of Five, N-[2-chloro-5-(trifluoromethyl)phenyl]-4-(piperidine-1-sulfonyl)benzamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-[2-chloro-5-(trifluoromethyl)phenyl]-4-(piperidine-1-sulfonyl)benzamide?
The CAS number of N-[2-chloro-5-(trifluoromethyl)phenyl]-4-(piperidine-1-sulfonyl)benzamide is 392289-88-2.
What is the molecular formula of N-[2-chloro-5-(trifluoromethyl)phenyl]-4-(piperidine-1-sulfonyl)benzamide?
The molecular formula of N-[2-chloro-5-(trifluoromethyl)phenyl]-4-(piperidine-1-sulfonyl)benzamide is C19H18ClF3N2O3S.
What is the molecular weight of N-[2-chloro-5-(trifluoromethyl)phenyl]-4-(piperidine-1-sulfonyl)benzamide?
The molecular weight of N-[2-chloro-5-(trifluoromethyl)phenyl]-4-(piperidine-1-sulfonyl)benzamide is 446.07 g/mol.
Where can I buy N-[2-chloro-5-(trifluoromethyl)phenyl]-4-(piperidine-1-sulfonyl)benzamide?
You can request a quote for N-[2-chloro-5-(trifluoromethyl)phenyl]-4-(piperidine-1-sulfonyl)benzamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-[2-chloro-5-(trifluoromethyl)phenyl]-4-(piperidine-1-sulfonyl)benzamide?
Yes, KEHONG BIO provides custom synthesis services for N-[2-chloro-5-(trifluoromethyl)phenyl]-4-(piperidine-1-sulfonyl)benzamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.