4-Chloro-6-fluoroquinoline
TL;DR: 4-Chloro-6-fluoroquinoline (CAS 391-77-5) is a chemical compound with molecular formula C9H5ClFN and molecular weight 181.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-chloro-6-fluoroquinoline
Also Known As: 4-Chloro-6-fluoroquinoline, 4-chloro-6-fluoro-quinoline, Quinoline, 4-chloro-6-fluoro-, 4-Chloro-6-fluoroquinolin, 6-fluoro-4-chloroquinoline
| Molecular Formula | C9H5ClFN |
|---|---|
| Molecular Weight | 181.01 g/mol |
| LogP | 3.0273 |
| Topological Polar Surface Area | 12.89 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 0 |
| Exact Mass | 181.00946 |
| Heavy Atoms | 12 |
| Complexity | 427.7981 |
Chemical Identifiers
| CAS Number | 391-77-5 |
|---|---|
| SMILES | C1=CC2=NC=CC(=C2C=C1F)Cl |
Product Overview
4-Chloro-6-fluoroquinoline (CAS 391-77-5), with molecular formula C9H5ClFN and molecular weight 181.01 g/mol. IUPAC: 4-chloro-6-fluoroquinoline.
Chemical Property Profile of 4-Chloro-6-fluoroquinoline
Property Insights of 4-Chloro-6-fluoroquinoline
The XLogP value of 3.0273 indicates that 4-Chloro-6-fluoroquinoline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 12.89 Ų, 4-Chloro-6-fluoroquinoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Chloro-6-fluoroquinoline has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Chloro-6-fluoroquinoline?
The CAS number of 4-Chloro-6-fluoroquinoline is 391-77-5.
What is the molecular formula of 4-Chloro-6-fluoroquinoline?
The molecular formula of 4-Chloro-6-fluoroquinoline is C9H5ClFN.
What is the molecular weight of 4-Chloro-6-fluoroquinoline?
The molecular weight of 4-Chloro-6-fluoroquinoline is 181.01 g/mol.
Where can I buy 4-Chloro-6-fluoroquinoline?
You can request a quote for 4-Chloro-6-fluoroquinoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Chloro-6-fluoroquinoline?
Yes, KEHONG BIO provides custom synthesis services for 4-Chloro-6-fluoroquinoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.