N-(((2S)-1-Butylpyrrolidin-2-yl)methyl)-4-cyano-1-methoxy-2-naphthamide
TL;DR: N-(((2S)-1-Butylpyrrolidin-2-yl)methyl)-4-cyano-1-methoxy-2-naphthamide (CAS 390412-29-0) is a chemical compound with molecular formula C22H27N3O2 and molecular weight 365.21 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[[(2S)-1-butylpyrrolidin-2-yl]methyl]-4-cyano-1-methoxynaphthalene-2-carboxamide
Also Known As: Nafadotride, N-(((2S)-1-Butylpyrrolidin-2-yl)methyl)-4-cyano-1-methoxy-2-naphthamide, N-[[(2S)-1-butylpyrrolidin-2-yl]methyl]-4-cyano-1-methoxynaphthalene-2-carboxamide, N-((n-butyl-2-pyrrolidinyl)methyl)-1-methoxy-4-cyanonaphthalene-2-carboxamide, N-[[(2S)-1-Butylpyrrolidin-2alpha-yl]methyl]-1-methoxy-4-cyanonaphthalene-2-carboxamide
| Molecular Formula | C22H27N3O2 |
|---|---|
| Molecular Weight | 365.21 g/mol |
| LogP | 3.71438 |
| Topological Polar Surface Area | 65.36 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 7 |
| Exact Mass | 365.21033 |
| Heavy Atoms | 27 |
| Complexity | 856.49207 |
Chemical Identifiers
| CAS Number | 390412-29-0 |
|---|---|
| SMILES | CCCCN1CCC[C@H]1CNC(=O)C2=C(C3=CC=CC=C3C(=C2)C#N)OC |
Product Overview
N-(((2S)-1-Butylpyrrolidin-2-yl)methyl)-4-cyano-1-methoxy-2-naphthamide (CAS 390412-29-0), with molecular formula C22H27N3O2 and molecular weight 365.21 g/mol. IUPAC: N-[[(2S)-1-butylpyrrolidin-2-yl]methyl]-4-cyano-1-methoxynaphthalene-2-carboxamide.
Chemical Property Profile of N-(((2S)-1-Butylpyrrolidin-2-yl)methyl)-4-cyano-1-methoxy-2-naphthamide
Property Insights of N-(((2S)-1-Butylpyrrolidin-2-yl)methyl)-4-cyano-1-methoxy-2-naphthamide
The XLogP value of 3.71438 indicates that N-(((2S)-1-Butylpyrrolidin-2-yl)methyl)-4-cyano-1-methoxy-2-naphthamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 65.36 Ų falls within the moderate polarity range, balancing permeability and solubility for N-(((2S)-1-Butylpyrrolidin-2-yl)methyl)-4-cyano-1-methoxy-2-naphthamide. Following Lipinski's Rule of Five, N-(((2S)-1-Butylpyrrolidin-2-yl)methyl)-4-cyano-1-methoxy-2-naphthamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(((2S)-1-Butylpyrrolidin-2-yl)methyl)-4-cyano-1-methoxy-2-naphthamide?
The CAS number of N-(((2S)-1-Butylpyrrolidin-2-yl)methyl)-4-cyano-1-methoxy-2-naphthamide is 390412-29-0.
What is the molecular formula of N-(((2S)-1-Butylpyrrolidin-2-yl)methyl)-4-cyano-1-methoxy-2-naphthamide?
The molecular formula of N-(((2S)-1-Butylpyrrolidin-2-yl)methyl)-4-cyano-1-methoxy-2-naphthamide is C22H27N3O2.
What is the molecular weight of N-(((2S)-1-Butylpyrrolidin-2-yl)methyl)-4-cyano-1-methoxy-2-naphthamide?
The molecular weight of N-(((2S)-1-Butylpyrrolidin-2-yl)methyl)-4-cyano-1-methoxy-2-naphthamide is 365.21 g/mol.
Where can I buy N-(((2S)-1-Butylpyrrolidin-2-yl)methyl)-4-cyano-1-methoxy-2-naphthamide?
You can request a quote for N-(((2S)-1-Butylpyrrolidin-2-yl)methyl)-4-cyano-1-methoxy-2-naphthamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(((2S)-1-Butylpyrrolidin-2-yl)methyl)-4-cyano-1-methoxy-2-naphthamide?
Yes, KEHONG BIO provides custom synthesis services for N-(((2S)-1-Butylpyrrolidin-2-yl)methyl)-4-cyano-1-methoxy-2-naphthamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.