Tenofovir Impurity 100
TL;DR: Tenofovir Impurity 100 (CAS 390409-29-7) is a chemical compound with molecular formula C19H25N6O5P and molecular weight 448.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
methyl (2S)-2-[[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-phenoxyphosphoryl]amino]propanoate
Also Known As: Tenofovir Impurity 100, Tenofovir Methyl Ester, Tenofovir alafenamide methyl ester, J1.523.218H, Methyl (((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-L-alaninate
| Molecular Formula | C19H25N6O5P |
|---|---|
| Molecular Weight | 448.16 g/mol |
| LogP | 2.1943 |
| Topological Polar Surface Area | 143.48 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 10 |
| Exact Mass | 448.1624 |
| Heavy Atoms | 31 |
| Complexity | 1076.0955 |
Chemical Identifiers
| CAS Number | 390409-29-7 |
|---|---|
| SMILES | C[C@H](CN1C=NC2=C(N=CN=C21)N)OCP(=O)(N[C@@H](C)C(=O)OC)OC3=CC=CC=C3 |
Product Overview
Tenofovir Impurity 100 (CAS 390409-29-7), with molecular formula C19H25N6O5P and molecular weight 448.16 g/mol. IUPAC: methyl (2S)-2-[[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-phenoxyphosphoryl]amino]propanoate.
Chemical Property Profile of Tenofovir Impurity 100
Property Insights of Tenofovir Impurity 100
The XLogP value of 2.1943 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Tenofovir Impurity 100. The TPSA of 143.48 Ų indicates high polarity, suggesting Tenofovir Impurity 100 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Tenofovir Impurity 100 has 2 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Tenofovir Impurity 100?
The CAS number of Tenofovir Impurity 100 is 390409-29-7.
What is the molecular formula of Tenofovir Impurity 100?
The molecular formula of Tenofovir Impurity 100 is C19H25N6O5P.
What is the molecular weight of Tenofovir Impurity 100?
The molecular weight of Tenofovir Impurity 100 is 448.16 g/mol.
Where can I buy Tenofovir Impurity 100?
You can request a quote for Tenofovir Impurity 100 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Tenofovir Impurity 100?
Yes, KEHONG BIO provides custom synthesis services for Tenofovir Impurity 100 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.