MeTRH
TL;DR: MeTRH (CAS 38983-06-1) is a chemical compound with molecular formula C17H24N6O4 and molecular weight 376.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-1-methyl-5-oxopyrrolidine-2-carboxamide
Also Known As: MeTRH, His(1-methyl)-TRH, Me-TRH, [3H]MeTRH, pGlu-His(1(t)-methyl)-ProNH2
| Molecular Formula | C17H24N6O4 |
|---|---|
| Molecular Weight | 376.19 g/mol |
| LogP | -1.4659 |
| Topological Polar Surface Area | 141.49 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 376.1859 |
| Heavy Atoms | 27 |
| Complexity | 733.7919 |
Chemical Identifiers
| CAS Number | 38983-06-1 |
|---|---|
| SMILES | CN1[C@@H](CCC1=O)C(=O)N[C@@H](CC2=CN=CN2)C(=O)N3CCC[C@H]3C(=O)N |
Product Overview
MeTRH (CAS 38983-06-1), with molecular formula C17H24N6O4 and molecular weight 376.19 g/mol. IUPAC: (2S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-1-methyl-5-oxopyrrolidine-2-carboxamide.
Chemical Property Profile of MeTRH
Property Insights of MeTRH
The XLogP value of -1.4659 indicates that MeTRH is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 141.49 Ų indicates high polarity, suggesting MeTRH may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, MeTRH has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of MeTRH?
The CAS number of MeTRH is 38983-06-1.
What is the molecular formula of MeTRH?
The molecular formula of MeTRH is C17H24N6O4.
What is the molecular weight of MeTRH?
The molecular weight of MeTRH is 376.19 g/mol.
Where can I buy MeTRH?
You can request a quote for MeTRH directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for MeTRH?
Yes, KEHONG BIO provides custom synthesis services for MeTRH and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.