FGFR2-IN-3
TL;DR: FGFR2-IN-3 (CAS 389629-38-3) is a chemical compound with molecular formula C28H22FN5O3 and molecular weight 495.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[7-(1H-benzimidazol-2-yl)-4-fluoro-1H-indol-3-yl]-2-(4-benzoylpiperazin-1-yl)ethane-1,2-dione
Also Known As: FGFR2-IN-3, 1-[7-(1H-benzimidazol-2-yl)-4-fluoro-1H-indol-3-yl]-2-(4-benzoylpiperazin-1-yl)ethane-1,2-dione, 1-[7-(1H-Benzimidazol-2-yl)-4-fluoro-1H-indol-3-yl]-2-(4-benzoylpiperazin-1-yl)-2-oxoethanone-
| Molecular Formula | C28H22FN5O3 |
|---|---|
| Molecular Weight | 495.17 g/mol |
| LogP | 3.6 |
| Topological Polar Surface Area | 102.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 495.17065 |
| Heavy Atoms | 37 |
| Complexity | 874.0 |
Chemical Identifiers
| CAS Number | 389629-38-3 |
|---|---|
| SMILES | C1CN(CCN1C(=O)C2=CC=CC=C2)C(=O)C(=O)C3=CNC4=C(C=CC(=C34)F)C5=NC6=CC=CC=C6N5 |
| InChIKey | AUWCFIZGHAFESH-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
FGFR2-IN-3 (CAS 389629-38-3), with molecular formula C28H22FN5O3 and molecular weight 495.17 g/mol. IUPAC: 1-[7-(1H-benzimidazol-2-yl)-4-fluoro-1H-indol-3-yl]-2-(4-benzoylpiperazin-1-yl)ethane-1,2-dione.
Chemical Property Profile of FGFR2-IN-3
Property Insights of FGFR2-IN-3
The XLogP value of 3.6 indicates that FGFR2-IN-3 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 102.0 Ų falls within the moderate polarity range, balancing permeability and solubility for FGFR2-IN-3. Following Lipinski's Rule of Five, FGFR2-IN-3 has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of FGFR2-IN-3?
The CAS number of FGFR2-IN-3 is 389629-38-3.
What is the molecular formula of FGFR2-IN-3?
The molecular formula of FGFR2-IN-3 is C28H22FN5O3.
What is the molecular weight of FGFR2-IN-3?
The molecular weight of FGFR2-IN-3 is 495.17 g/mol.
Where can I buy FGFR2-IN-3?
You can request a quote for FGFR2-IN-3 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for FGFR2-IN-3?
Yes, KEHONG BIO provides custom synthesis services for FGFR2-IN-3 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.