5-Iodouracil, TMS
TL;DR: 5-Iodouracil, TMS (CAS 38953-72-9) is a chemical compound with molecular formula C10H19IN2O2Si2 and molecular weight 382.00 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5-iodo-2-trimethylsilyloxypyrimidin-4-yl)oxy-trimethylsilane
Also Known As: 5-Iodouracil, TMS, Uracil, 5-iodo, TMS, 5-iodo-2,4-bis-O-trimethylsilyluracil, Pyrimidine, 2,4-dihydroxy-5-iodo, TMS, (5-iodo-2-trimethylsilyloxypyrimidin-4-yl)oxy-trimethylsilane
| Molecular Formula | C10H19IN2O2Si2 |
|---|---|
| Molecular Weight | 382.00 g/mol |
| LogP | 3.5086 |
| Topological Polar Surface Area | 44.2 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 382.003 |
| Heavy Atoms | 17 |
| Complexity | 256.0 |
Chemical Identifiers
| CAS Number | 38953-72-9 |
|---|---|
| SMILES | C[Si](C)(C)OC1=NC(=NC=C1I)O[Si](C)(C)C |
| InChIKey | PQSFYGJEXZRHMO-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
5-Iodouracil, TMS (CAS 38953-72-9), with molecular formula C10H19IN2O2Si2 and molecular weight 382.00 g/mol. IUPAC: (5-iodo-2-trimethylsilyloxypyrimidin-4-yl)oxy-trimethylsilane.
Chemical Property Profile of 5-Iodouracil, TMS
Property Insights of 5-Iodouracil, TMS
The XLogP value of 3.5086 indicates that 5-Iodouracil, TMS is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 44.2 Ų, 5-Iodouracil, TMS exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-Iodouracil, TMS has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-Iodouracil, TMS?
The CAS number of 5-Iodouracil, TMS is 38953-72-9.
What is the molecular formula of 5-Iodouracil, TMS?
The molecular formula of 5-Iodouracil, TMS is C10H19IN2O2Si2.
What is the molecular weight of 5-Iodouracil, TMS?
The molecular weight of 5-Iodouracil, TMS is 382.00 g/mol.
Where can I buy 5-Iodouracil, TMS?
You can request a quote for 5-Iodouracil, TMS directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-Iodouracil, TMS?
Yes, KEHONG BIO provides custom synthesis services for 5-Iodouracil, TMS and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.