(E)-N'-((4-chloro-2-oxo-3-phenyl-2,3-dihydrothiazol-5-yl)methylene)isonicotinohydrazide
TL;DR: (E)-N'-((4-chloro-2-oxo-3-phenyl-2,3-dihydrothiazol-5-yl)methylene)isonicotinohydrazide (CAS 388606-02-8) is a chemical compound with molecular formula C16H11ClN4O2S and molecular weight 358.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(E)-(4-chloro-2-oxo-3-phenyl-1,3-thiazol-5-yl)methylideneamino]pyridine-4-carboxamide
Also Known As: (E)-N'-((4-chloro-2-oxo-3-phenyl-2,3-dihydrothiazol-5-yl)methylene)isonicotinohydrazide, N-[(E)-(4-chloro-2-oxo-3-phenyl-1,3-thiazol-5-yl)methylideneamino]pyridine-4-carboxamide, Isonicotinic acid [1-(4-chloro-2-oxo-3-phenyl-2,3-dihydro-thiazol-5-yl)-meth-(E)-ylidene]-hydrazide, N'-[(E)-(4-chloro-2-oxo-3-phenyl-2,3-dihydro-1,3-thiazol-5-yl)methylidene]pyridine-4-carbohydrazide, N-[(1E)-2-(4-chloro-2-oxo-3-phenyl(1,3-thiazolin-5-yl))-1-azavinyl]-4-pyridylc arboxamide
| Molecular Formula | C16H11ClN4O2S |
|---|---|
| Molecular Weight | 358.03 g/mol |
| LogP | 2.7113 |
| Topological Polar Surface Area | 76.35 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 358.0291 |
| Heavy Atoms | 24 |
| Complexity | 935.7162 |
Chemical Identifiers
| CAS Number | 388606-02-8 |
|---|---|
| SMILES | C1=CC=C(C=C1)N2C(=C(SC2=O)/C=N/NC(=O)C3=CC=NC=C3)Cl |
Product Overview
(E)-N'-((4-chloro-2-oxo-3-phenyl-2,3-dihydrothiazol-5-yl)methylene)isonicotinohydrazide (CAS 388606-02-8), with molecular formula C16H11ClN4O2S and molecular weight 358.03 g/mol. IUPAC: N-[(E)-(4-chloro-2-oxo-3-phenyl-1,3-thiazol-5-yl)methylideneamino]pyridine-4-carboxamide.
Chemical Property Profile of (E)-N'-((4-chloro-2-oxo-3-phenyl-2,3-dihydrothiazol-5-yl)methylene)isonicotinohydrazide
Property Insights of (E)-N'-((4-chloro-2-oxo-3-phenyl-2,3-dihydrothiazol-5-yl)methylene)isonicotinohydrazide
The XLogP value of 2.7113 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (E)-N'-((4-chloro-2-oxo-3-phenyl-2,3-dihydrothiazol-5-yl)methylene)isonicotinohydrazide. The TPSA of 76.35 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-N'-((4-chloro-2-oxo-3-phenyl-2,3-dihydrothiazol-5-yl)methylene)isonicotinohydrazide. Following Lipinski's Rule of Five, (E)-N'-((4-chloro-2-oxo-3-phenyl-2,3-dihydrothiazol-5-yl)methylene)isonicotinohydrazide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-N'-((4-chloro-2-oxo-3-phenyl-2,3-dihydrothiazol-5-yl)methylene)isonicotinohydrazide?
The CAS number of (E)-N'-((4-chloro-2-oxo-3-phenyl-2,3-dihydrothiazol-5-yl)methylene)isonicotinohydrazide is 388606-02-8.
What is the molecular formula of (E)-N'-((4-chloro-2-oxo-3-phenyl-2,3-dihydrothiazol-5-yl)methylene)isonicotinohydrazide?
The molecular formula of (E)-N'-((4-chloro-2-oxo-3-phenyl-2,3-dihydrothiazol-5-yl)methylene)isonicotinohydrazide is C16H11ClN4O2S.
What is the molecular weight of (E)-N'-((4-chloro-2-oxo-3-phenyl-2,3-dihydrothiazol-5-yl)methylene)isonicotinohydrazide?
The molecular weight of (E)-N'-((4-chloro-2-oxo-3-phenyl-2,3-dihydrothiazol-5-yl)methylene)isonicotinohydrazide is 358.03 g/mol.
Where can I buy (E)-N'-((4-chloro-2-oxo-3-phenyl-2,3-dihydrothiazol-5-yl)methylene)isonicotinohydrazide?
You can request a quote for (E)-N'-((4-chloro-2-oxo-3-phenyl-2,3-dihydrothiazol-5-yl)methylene)isonicotinohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-N'-((4-chloro-2-oxo-3-phenyl-2,3-dihydrothiazol-5-yl)methylene)isonicotinohydrazide?
Yes, KEHONG BIO provides custom synthesis services for (E)-N'-((4-chloro-2-oxo-3-phenyl-2,3-dihydrothiazol-5-yl)methylene)isonicotinohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.