![5-chloro-3-[(4-fluorophenyl)methylidene]-1H-indol-2-one structure](/static/products/387/387343-08-0.png)
5-chloro-3-[(4-fluorophenyl)methylidene]-1H-indol-2-one
TL;DR: 5-chloro-3-[(4-fluorophenyl)methylidene]-1H-indol-2-one (CAS 387343-08-0) is a chemical compound with molecular formula C15H9ClFNO and molecular weight 273.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-chloro-3-[(4-fluorophenyl)methylidene]-1H-indol-2-one
Also Known As: 5-chloro-3-[(4-fluorophenyl)methylidene]-1H-indol-2-one, (3E)-5-Chloro-3-(4-fluorobenzylidene)-1,3-dihydro-2H-indol-2
| Molecular Formula | C15H9ClFNO |
|---|---|
| Molecular Weight | 273.04 g/mol |
| LogP | 3.9718 |
| Topological Polar Surface Area | 29.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 1 |
| Exact Mass | 273.03568 |
| Heavy Atoms | 19 |
| Complexity | 691.7918 |
Chemical Identifiers
| CAS Number | 387343-08-0 |
|---|---|
| SMILES | C1=CC(=CC=C1C=C2C3=C(C=CC(=C3)Cl)NC2=O)F |
Product Overview
5-chloro-3-[(4-fluorophenyl)methylidene]-1H-indol-2-one (CAS 387343-08-0), with molecular formula C15H9ClFNO and molecular weight 273.04 g/mol. IUPAC: 5-chloro-3-[(4-fluorophenyl)methylidene]-1H-indol-2-one.
Chemical Property Profile of 5-chloro-3-[(4-fluorophenyl)methylidene]-1H-indol-2-one
Property Insights of 5-chloro-3-[(4-fluorophenyl)methylidene]-1H-indol-2-one
The XLogP value of 3.9718 indicates that 5-chloro-3-[(4-fluorophenyl)methylidene]-1H-indol-2-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 29.1 Ų, 5-chloro-3-[(4-fluorophenyl)methylidene]-1H-indol-2-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-chloro-3-[(4-fluorophenyl)methylidene]-1H-indol-2-one has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-chloro-3-[(4-fluorophenyl)methylidene]-1H-indol-2-one?
The CAS number of 5-chloro-3-[(4-fluorophenyl)methylidene]-1H-indol-2-one is 387343-08-0.
What is the molecular formula of 5-chloro-3-[(4-fluorophenyl)methylidene]-1H-indol-2-one?
The molecular formula of 5-chloro-3-[(4-fluorophenyl)methylidene]-1H-indol-2-one is C15H9ClFNO.
What is the molecular weight of 5-chloro-3-[(4-fluorophenyl)methylidene]-1H-indol-2-one?
The molecular weight of 5-chloro-3-[(4-fluorophenyl)methylidene]-1H-indol-2-one is 273.04 g/mol.
Where can I buy 5-chloro-3-[(4-fluorophenyl)methylidene]-1H-indol-2-one?
You can request a quote for 5-chloro-3-[(4-fluorophenyl)methylidene]-1H-indol-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-chloro-3-[(4-fluorophenyl)methylidene]-1H-indol-2-one?
Yes, KEHONG BIO provides custom synthesis services for 5-chloro-3-[(4-fluorophenyl)methylidene]-1H-indol-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.