Ethyl ((4-fluorophenyl)(hydroxy)methyl)(phenylethynyl)phosphinate structure

Ethyl ((4-fluorophenyl)(hydroxy)methyl)(phenylethynyl)phosphinate

TL;DR: Ethyl ((4-fluorophenyl)(hydroxy)methyl)(phenylethynyl)phosphinate (CAS 385417-33-4) is a chemical compound with molecular formula C17H16FO3P and molecular weight 318.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[ethoxy(2-phenylethynyl)phosphoryl]-(4-fluorophenyl)methanol

Also Known As: [ethoxy(2-phenylethynyl)phosphoryl]-(4-fluorophenyl)methanol|ethyl ((4-fluorophenyl)(hydroxy)methyl)(phenylethynyl)phosphinate|ethyl [(4-fluorophenyl)(hydroxy)methyl](phenylethynyl)phosphinate

CAS: 385417-33-4
Molecular Formula C17H16FO3P
Molecular Weight 318.08 g/mol
LogP 4.1404
Topological Polar Surface Area 46.53 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 3
Rotatable Bonds 4
Exact Mass 318.08212
Heavy Atoms 22
Complexity 717.06445

Chemical Identifiers

CAS Number 385417-33-4
SMILES CCOP(=O)(C#CC1=CC=CC=C1)C(C2=CC=C(C=C2)F)O

Product Overview

Ethyl ((4-fluorophenyl)(hydroxy)methyl)(phenylethynyl)phosphinate (CAS 385417-33-4), with molecular formula C17H16FO3P and molecular weight 318.08 g/mol. IUPAC: [ethoxy(2-phenylethynyl)phosphoryl]-(4-fluorophenyl)methanol.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of Ethyl ((4-fluorophenyl)(hydroxy)methyl)(phenylethynyl)phosphinate

XLogP
4.1404
TPSA (Topological Polar Surface Area)
46.53
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
3
Rotatable Bonds
4
Heavy Atoms
22
Complexity
717.06445
Exact Mass
318.08212
Monoisotopic Mass
318.08212
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Ethyl ((4-fluorophenyl)(hydroxy)methyl)(phenylethynyl)phosphinate

The XLogP value of 4.1404 indicates that Ethyl ((4-fluorophenyl)(hydroxy)methyl)(phenylethynyl)phosphinate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 46.53 Ų, Ethyl ((4-fluorophenyl)(hydroxy)methyl)(phenylethynyl)phosphinate exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Ethyl ((4-fluorophenyl)(hydroxy)methyl)(phenylethynyl)phosphinate has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Ethyl ((4-fluorophenyl)(hydroxy)methyl)(phenylethynyl)phosphinate?

The CAS number of Ethyl ((4-fluorophenyl)(hydroxy)methyl)(phenylethynyl)phosphinate is 385417-33-4.

What is the molecular formula of Ethyl ((4-fluorophenyl)(hydroxy)methyl)(phenylethynyl)phosphinate?

The molecular formula of Ethyl ((4-fluorophenyl)(hydroxy)methyl)(phenylethynyl)phosphinate is C17H16FO3P.

What is the molecular weight of Ethyl ((4-fluorophenyl)(hydroxy)methyl)(phenylethynyl)phosphinate?

The molecular weight of Ethyl ((4-fluorophenyl)(hydroxy)methyl)(phenylethynyl)phosphinate is 318.08 g/mol.

Where can I buy Ethyl ((4-fluorophenyl)(hydroxy)methyl)(phenylethynyl)phosphinate?

You can request a quote for Ethyl ((4-fluorophenyl)(hydroxy)methyl)(phenylethynyl)phosphinate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Ethyl ((4-fluorophenyl)(hydroxy)methyl)(phenylethynyl)phosphinate?

Yes, KEHONG BIO provides custom synthesis services for Ethyl ((4-fluorophenyl)(hydroxy)methyl)(phenylethynyl)phosphinate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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