8-(Difluoromethoxy)quinoline
TL;DR: 8-(Difluoromethoxy)quinoline (CAS 385382-46-7) is a chemical compound with molecular formula C10H7F2NO and molecular weight 195.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
8-(difluoromethoxy)quinoline
Also Known As: 8-(difluoromethoxy)quinoline, Quinoline, 8-(difluoromethoxy)-, difluoro-8-quinolyloxymethane, J3.274.334J
| Molecular Formula | C10H7F2NO |
|---|---|
| Molecular Weight | 195.05 g/mol |
| LogP | 2.8362 |
| Topological Polar Surface Area | 22.12 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 195.04958 |
| Heavy Atoms | 14 |
| Complexity | 439.57498 |
Chemical Identifiers
| CAS Number | 385382-46-7 |
|---|---|
| SMILES | C1=CC2=C(C(=C1)OC(F)F)N=CC=C2 |
Product Overview
8-(Difluoromethoxy)quinoline (CAS 385382-46-7), with molecular formula C10H7F2NO and molecular weight 195.05 g/mol. IUPAC: 8-(difluoromethoxy)quinoline.
Chemical Property Profile of 8-(Difluoromethoxy)quinoline
Property Insights of 8-(Difluoromethoxy)quinoline
The XLogP value of 2.8362 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 8-(Difluoromethoxy)quinoline. With a topological polar surface area (TPSA) of 22.12 Ų, 8-(Difluoromethoxy)quinoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 8-(Difluoromethoxy)quinoline has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8-(Difluoromethoxy)quinoline?
The CAS number of 8-(Difluoromethoxy)quinoline is 385382-46-7.
What is the molecular formula of 8-(Difluoromethoxy)quinoline?
The molecular formula of 8-(Difluoromethoxy)quinoline is C10H7F2NO.
What is the molecular weight of 8-(Difluoromethoxy)quinoline?
The molecular weight of 8-(Difluoromethoxy)quinoline is 195.05 g/mol.
Where can I buy 8-(Difluoromethoxy)quinoline?
You can request a quote for 8-(Difluoromethoxy)quinoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8-(Difluoromethoxy)quinoline?
Yes, KEHONG BIO provides custom synthesis services for 8-(Difluoromethoxy)quinoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.