AF-399/40805030
TL;DR: AF-399/40805030 (CAS 385374-09-4) is a chemical compound with molecular formula C18H14FN3O2S and molecular weight 355.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-(4-fluorophenyl)-2-(4-methoxyphenyl)-5,6-dihydro-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one
Also Known As: AF-399/40805030, 5-(4-fluorophenyl)-2-(4-methoxyphenyl)-5,6-dihydro-7H-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one, 5-(4-fluorophenyl)-2-(4-methoxyphenyl)-5,6-dihydro-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one, 5-(4-FLUOROPHENYL)-2-(4-METHOXYPHENYL)-5H,6H,7H-[1,2,4]TRIAZOLO[3,2-B][1,3]THIAZIN-7-ONE, 5-(4-fluorophenyl)-2-(4-methoxyphenyl)-5H,6H-1,2,4-triazolo[5,1-b]1,3-thiazape rhydroin-7-one
| Molecular Formula | C18H14FN3O2S |
|---|---|
| Molecular Weight | 355.08 g/mol |
| LogP | 3.9701 |
| Topological Polar Surface Area | 57.01 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 355.07907 |
| Heavy Atoms | 25 |
| Complexity | 922.49915 |
Chemical Identifiers
| CAS Number | 385374-09-4 |
|---|---|
| SMILES | COC1=CC=C(C=C1)C2=NN3C(=O)CC(SC3=N2)C4=CC=C(C=C4)F |
Product Overview
AF-399/40805030 (CAS 385374-09-4), with molecular formula C18H14FN3O2S and molecular weight 355.08 g/mol. IUPAC: 5-(4-fluorophenyl)-2-(4-methoxyphenyl)-5,6-dihydro-[1,2,4]triazolo[5,1-b][1,3]thiazin-7-one.
Chemical Property Profile of AF-399/40805030
Property Insights of AF-399/40805030
The XLogP value of 3.9701 indicates that AF-399/40805030 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.01 Ų, AF-399/40805030 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, AF-399/40805030 has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AF-399/40805030?
The CAS number of AF-399/40805030 is 385374-09-4.
What is the molecular formula of AF-399/40805030?
The molecular formula of AF-399/40805030 is C18H14FN3O2S.
What is the molecular weight of AF-399/40805030?
The molecular weight of AF-399/40805030 is 355.08 g/mol.
Where can I buy AF-399/40805030?
You can request a quote for AF-399/40805030 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AF-399/40805030?
Yes, KEHONG BIO provides custom synthesis services for AF-399/40805030 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.