Proline chloromethyl ketone
TL;DR: Proline chloromethyl ketone (CAS 38491-75-7) is a chemical compound with molecular formula C6H10ClNO and molecular weight 147.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-chloro-1-[(2S)-pyrrolidin-2-yl]ethanone
Also Known As: Proline chloromethyl ketone, Pro-chloromethyl ketone, L-Proline chloromethyl ketone, 2-chloro-1-[(2S)-pyrrolidin-2-yl]ethan-1-one, 2-chloro-1-[(2S)-pyrrolidin-2-yl]ethanone
| Molecular Formula | C6H10ClNO |
|---|---|
| Molecular Weight | 147.05 g/mol |
| LogP | 0.7 |
| Topological Polar Surface Area | 29.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 147.04509 |
| Heavy Atoms | 9 |
| Complexity | 116.0 |
Chemical Identifiers
| CAS Number | 38491-75-7 |
|---|---|
| SMILES | C1C[C@H](NC1)C(=O)CCl |
| InChIKey | YGAFBOIEHARROZ-YFKPBYRVSA-N |
Product Overview
Proline chloromethyl ketone (CAS 38491-75-7), with molecular formula C6H10ClNO and molecular weight 147.05 g/mol. IUPAC: 2-chloro-1-[(2S)-pyrrolidin-2-yl]ethanone.
Chemical Property Profile of Proline chloromethyl ketone
Property Insights of Proline chloromethyl ketone
The XLogP value of 0.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Proline chloromethyl ketone. With a topological polar surface area (TPSA) of 29.1 Ų, Proline chloromethyl ketone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Proline chloromethyl ketone has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Proline chloromethyl ketone?
The CAS number of Proline chloromethyl ketone is 38491-75-7.
What is the molecular formula of Proline chloromethyl ketone?
The molecular formula of Proline chloromethyl ketone is C6H10ClNO.
What is the molecular weight of Proline chloromethyl ketone?
The molecular weight of Proline chloromethyl ketone is 147.05 g/mol.
Where can I buy Proline chloromethyl ketone?
You can request a quote for Proline chloromethyl ketone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Proline chloromethyl ketone?
Yes, KEHONG BIO provides custom synthesis services for Proline chloromethyl ketone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.