(E)-3-(1H-indol-3-yl)-1-thiophen-2-ylprop-2-en-1-one
TL;DR: (E)-3-(1H-indol-3-yl)-1-thiophen-2-ylprop-2-en-1-one (CAS 38470-80-3) is a chemical compound with molecular formula C15H11NOS and molecular weight 253.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-3-(1H-indol-3-yl)-1-thiophen-2-ylprop-2-en-1-one
Also Known As: BAS 00801832, 3-(1H-Indol-3-yl)-1-thiophen-2-yl-propenone, (E)-3-(1H-indol-3-yl)-1-thiophen-2-ylprop-2-en-1-one, (2E)-3-(1H-indol-3-yl)-1-(thiophen-2-yl)prop-2-en-1-one, (E)-3-(1H-indol-3-yl)-1-(thiophen-2-yl)prop-2-en-1-one
| Molecular Formula | C15H11NOS |
|---|---|
| Molecular Weight | 253.06 g/mol |
| LogP | 4.1255 |
| Topological Polar Surface Area | 32.86 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 253.05614 |
| Heavy Atoms | 18 |
| Complexity | 707.01575 |
Chemical Identifiers
| CAS Number | 38470-80-3 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C(=CN2)/C=C/C(=O)C3=CC=CS3 |
Product Overview
(E)-3-(1H-indol-3-yl)-1-thiophen-2-ylprop-2-en-1-one (CAS 38470-80-3), with molecular formula C15H11NOS and molecular weight 253.06 g/mol. IUPAC: (E)-3-(1H-indol-3-yl)-1-thiophen-2-ylprop-2-en-1-one.
Chemical Property Profile of (E)-3-(1H-indol-3-yl)-1-thiophen-2-ylprop-2-en-1-one
Property Insights of (E)-3-(1H-indol-3-yl)-1-thiophen-2-ylprop-2-en-1-one
The XLogP value of 4.1255 indicates that (E)-3-(1H-indol-3-yl)-1-thiophen-2-ylprop-2-en-1-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 32.86 Ų, (E)-3-(1H-indol-3-yl)-1-thiophen-2-ylprop-2-en-1-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-3-(1H-indol-3-yl)-1-thiophen-2-ylprop-2-en-1-one has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-3-(1H-indol-3-yl)-1-thiophen-2-ylprop-2-en-1-one?
The CAS number of (E)-3-(1H-indol-3-yl)-1-thiophen-2-ylprop-2-en-1-one is 38470-80-3.
What is the molecular formula of (E)-3-(1H-indol-3-yl)-1-thiophen-2-ylprop-2-en-1-one?
The molecular formula of (E)-3-(1H-indol-3-yl)-1-thiophen-2-ylprop-2-en-1-one is C15H11NOS.
What is the molecular weight of (E)-3-(1H-indol-3-yl)-1-thiophen-2-ylprop-2-en-1-one?
The molecular weight of (E)-3-(1H-indol-3-yl)-1-thiophen-2-ylprop-2-en-1-one is 253.06 g/mol.
Where can I buy (E)-3-(1H-indol-3-yl)-1-thiophen-2-ylprop-2-en-1-one?
You can request a quote for (E)-3-(1H-indol-3-yl)-1-thiophen-2-ylprop-2-en-1-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-3-(1H-indol-3-yl)-1-thiophen-2-ylprop-2-en-1-one?
Yes, KEHONG BIO provides custom synthesis services for (E)-3-(1H-indol-3-yl)-1-thiophen-2-ylprop-2-en-1-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.