AF-399/41115280
TL;DR: AF-399/41115280 (CAS 384377-27-9) is a chemical compound with molecular formula C23H17FN2O3 and molecular weight 388.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4E)-5-(4-fluorophenyl)-4-[hydroxy(phenyl)methylidene]-1-(6-methyl-2-pyridinyl)pyrrolidine-2,3-dione
Also Known As: AF-399/41115280, 4-benzoyl-5-(4-fluorophenyl)-3-hydroxy-1-(6-methylpyridin-2-yl)-1H-pyrrol-2(5H)-one, (4E)-5-(4-fluorophenyl)-4-[hydroxy(phenyl)methylidene]-1-(6-methylpyridin-2-yl)pyrrolidine-2,3-dione, (E)-[2-(4-fluorophenyl)-1-(6-methylpyridinium-2-yl)-4,5-dioxopyrrolidin-3-ylidene](phenyl)methanolate, 4-benzoyl-5-(4-fluorophenyl)-3-hydroxy-1-(6-methyl-2-pyridinyl)-1,5-dihydro-2H-pyrrol-2-one
| Molecular Formula | C23H17FN2O3 |
|---|---|
| Molecular Weight | 388.12 g/mol |
| LogP | 4.15542 |
| Topological Polar Surface Area | 70.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 388.1223 |
| Heavy Atoms | 29 |
| Complexity | 1124.3746 |
Chemical Identifiers
| CAS Number | 384377-27-9 |
|---|---|
| SMILES | CC1=NC(=CC=C1)N2C(/C(=C(/C3=CC=CC=C3)\O)/C(=O)C2=O)C4=CC=C(C=C4)F |
Product Overview
AF-399/41115280 (CAS 384377-27-9), with molecular formula C23H17FN2O3 and molecular weight 388.12 g/mol. IUPAC: (4E)-5-(4-fluorophenyl)-4-[hydroxy(phenyl)methylidene]-1-(6-methyl-2-pyridinyl)pyrrolidine-2,3-dione.
Chemical Property Profile of AF-399/41115280
Property Insights of AF-399/41115280
The XLogP value of 4.15542 indicates that AF-399/41115280 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 70.5 Ų falls within the moderate polarity range, balancing permeability and solubility for AF-399/41115280. Following Lipinski's Rule of Five, AF-399/41115280 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AF-399/41115280?
The CAS number of AF-399/41115280 is 384377-27-9.
What is the molecular formula of AF-399/41115280?
The molecular formula of AF-399/41115280 is C23H17FN2O3.
What is the molecular weight of AF-399/41115280?
The molecular weight of AF-399/41115280 is 388.12 g/mol.
Where can I buy AF-399/41115280?
You can request a quote for AF-399/41115280 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AF-399/41115280?
Yes, KEHONG BIO provides custom synthesis services for AF-399/41115280 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.