(2E)-2-(1-cyclopropylethylidene)-N-(4-fluorophenyl)hydrazinecarbothioamide
TL;DR: (2E)-2-(1-cyclopropylethylidene)-N-(4-fluorophenyl)hydrazinecarbothioamide (CAS 384375-68-2) is a chemical compound with molecular formula C12H14FN3S and molecular weight 251.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(E)-1-cyclopropylethylideneamino]-3-(4-fluorophenyl)thiourea
Also Known As: 1-[(E)-1-cyclopropylethylideneamino]-3-(4-fluorophenyl)thiourea, (2E)-2-(1-cyclopropylethylidene)-N-(4-fluorophenyl)hydrazinecarbothioamide, (E)-2-(1-cyclopropylethylidene)-N-(4-fluorophenyl)hydrazinecarbothioamide, 2-[(E)-1-CYCLOPROPYLETHYLIDENE]-N~1~-(4-FLUOROPHENYL)-1-HYDRAZINECARBOTHIOAMIDE
| Molecular Formula | C12H14FN3S |
|---|---|
| Molecular Weight | 251.09 g/mol |
| LogP | 2.898 |
| Topological Polar Surface Area | 36.42 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 251.08925 |
| Heavy Atoms | 17 |
| Complexity | 437.56888 |
Chemical Identifiers
| CAS Number | 384375-68-2 |
|---|---|
| SMILES | C/C(=N\NC(=S)NC1=CC=C(C=C1)F)/C2CC2 |
Product Overview
(2E)-2-(1-cyclopropylethylidene)-N-(4-fluorophenyl)hydrazinecarbothioamide (CAS 384375-68-2), with molecular formula C12H14FN3S and molecular weight 251.09 g/mol. IUPAC: 1-[(E)-1-cyclopropylethylideneamino]-3-(4-fluorophenyl)thiourea.
Chemical Property Profile of (2E)-2-(1-cyclopropylethylidene)-N-(4-fluorophenyl)hydrazinecarbothioamide
Property Insights of (2E)-2-(1-cyclopropylethylidene)-N-(4-fluorophenyl)hydrazinecarbothioamide
The XLogP value of 2.898 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (2E)-2-(1-cyclopropylethylidene)-N-(4-fluorophenyl)hydrazinecarbothioamide. With a topological polar surface area (TPSA) of 36.42 Ų, (2E)-2-(1-cyclopropylethylidene)-N-(4-fluorophenyl)hydrazinecarbothioamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (2E)-2-(1-cyclopropylethylidene)-N-(4-fluorophenyl)hydrazinecarbothioamide has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (2E)-2-(1-cyclopropylethylidene)-N-(4-fluorophenyl)hydrazinecarbothioamide?
The CAS number of (2E)-2-(1-cyclopropylethylidene)-N-(4-fluorophenyl)hydrazinecarbothioamide is 384375-68-2.
What is the molecular formula of (2E)-2-(1-cyclopropylethylidene)-N-(4-fluorophenyl)hydrazinecarbothioamide?
The molecular formula of (2E)-2-(1-cyclopropylethylidene)-N-(4-fluorophenyl)hydrazinecarbothioamide is C12H14FN3S.
What is the molecular weight of (2E)-2-(1-cyclopropylethylidene)-N-(4-fluorophenyl)hydrazinecarbothioamide?
The molecular weight of (2E)-2-(1-cyclopropylethylidene)-N-(4-fluorophenyl)hydrazinecarbothioamide is 251.09 g/mol.
Where can I buy (2E)-2-(1-cyclopropylethylidene)-N-(4-fluorophenyl)hydrazinecarbothioamide?
You can request a quote for (2E)-2-(1-cyclopropylethylidene)-N-(4-fluorophenyl)hydrazinecarbothioamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (2E)-2-(1-cyclopropylethylidene)-N-(4-fluorophenyl)hydrazinecarbothioamide?
Yes, KEHONG BIO provides custom synthesis services for (2E)-2-(1-cyclopropylethylidene)-N-(4-fluorophenyl)hydrazinecarbothioamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.