![(Z)-isopropyl 7-methyl-2-(3-nitrobenzylidene)-3-oxo-5-(p-tolyl)-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate structure](/static/products/384/384366-40-9.png)
(Z)-isopropyl 7-methyl-2-(3-nitrobenzylidene)-3-oxo-5-(p-tolyl)-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate
TL;DR: (Z)-isopropyl 7-methyl-2-(3-nitrobenzylidene)-3-oxo-5-(p-tolyl)-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate (CAS 384366-40-9) is a chemical compound with molecular formula C25H23N3O5S and molecular weight 477.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
propan-2-yl (2Z)-7-methyl-5-(4-methylphenyl)-2-[(3-nitrophenyl)methylidene]-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
Also Known As: (Z)-isopropyl 7-methyl-2-(3-nitrobenzylidene)-3-oxo-5-(p-tolyl)-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate, methylethyl 7-methyl-5-(4-methylphenyl)-2-[(3-nitrophenyl)methylene]-3-oxo-4,5 -dihydro-1,3-thiazolidino[3,2-a]pyrimidine-6-carboxylate, propan-2-yl (2Z)-7-methyl-5-(4-methylphenyl)-2-(3-nitrobenzylidene)-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate, propan-2-yl (2Z)-7-methyl-5-(4-methylphenyl)-2-[(3-nitrophenyl)methylidene]-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate
| Molecular Formula | C25H23N3O5S |
|---|---|
| Molecular Weight | 477.14 g/mol |
| LogP | 3.40342 |
| Topological Polar Surface Area | 103.8 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 5 |
| Exact Mass | 477.13583 |
| Heavy Atoms | 34 |
| Complexity | 1496.4786 |
Chemical Identifiers
| CAS Number | 384366-40-9 |
|---|---|
| SMILES | CC1=CC=C(C=C1)C2C(=C(N=C3N2C(=O)/C(=C/C4=CC(=CC=C4)[N+](=O)[O-])/S3)C)C(=O)OC(C)C |
Product Overview
(Z)-isopropyl 7-methyl-2-(3-nitrobenzylidene)-3-oxo-5-(p-tolyl)-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate (CAS 384366-40-9), with molecular formula C25H23N3O5S and molecular weight 477.14 g/mol. IUPAC: propan-2-yl (2Z)-7-methyl-5-(4-methylphenyl)-2-[(3-nitrophenyl)methylidene]-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate.
Chemical Property Profile of (Z)-isopropyl 7-methyl-2-(3-nitrobenzylidene)-3-oxo-5-(p-tolyl)-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate
Property Insights of (Z)-isopropyl 7-methyl-2-(3-nitrobenzylidene)-3-oxo-5-(p-tolyl)-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate
The XLogP value of 3.40342 indicates that (Z)-isopropyl 7-methyl-2-(3-nitrobenzylidene)-3-oxo-5-(p-tolyl)-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 103.8 Ų falls within the moderate polarity range, balancing permeability and solubility for (Z)-isopropyl 7-methyl-2-(3-nitrobenzylidene)-3-oxo-5-(p-tolyl)-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate. Following Lipinski's Rule of Five, (Z)-isopropyl 7-methyl-2-(3-nitrobenzylidene)-3-oxo-5-(p-tolyl)-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate has 0 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (Z)-isopropyl 7-methyl-2-(3-nitrobenzylidene)-3-oxo-5-(p-tolyl)-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate?
The CAS number of (Z)-isopropyl 7-methyl-2-(3-nitrobenzylidene)-3-oxo-5-(p-tolyl)-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate is 384366-40-9.
What is the molecular formula of (Z)-isopropyl 7-methyl-2-(3-nitrobenzylidene)-3-oxo-5-(p-tolyl)-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate?
The molecular formula of (Z)-isopropyl 7-methyl-2-(3-nitrobenzylidene)-3-oxo-5-(p-tolyl)-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate is C25H23N3O5S.
What is the molecular weight of (Z)-isopropyl 7-methyl-2-(3-nitrobenzylidene)-3-oxo-5-(p-tolyl)-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate?
The molecular weight of (Z)-isopropyl 7-methyl-2-(3-nitrobenzylidene)-3-oxo-5-(p-tolyl)-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate is 477.14 g/mol.
Where can I buy (Z)-isopropyl 7-methyl-2-(3-nitrobenzylidene)-3-oxo-5-(p-tolyl)-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate?
You can request a quote for (Z)-isopropyl 7-methyl-2-(3-nitrobenzylidene)-3-oxo-5-(p-tolyl)-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (Z)-isopropyl 7-methyl-2-(3-nitrobenzylidene)-3-oxo-5-(p-tolyl)-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate?
Yes, KEHONG BIO provides custom synthesis services for (Z)-isopropyl 7-methyl-2-(3-nitrobenzylidene)-3-oxo-5-(p-tolyl)-3,5-dihydro-2H-thiazolo[3,2-a]pyrimidine-6-carboxylate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.