![(E)-5-((((4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)methyl)amino)methylene)-1-(p-tolyl)pyrimidine-2,4,6(1H,3H,5H)-trione structure](/static/products/384/384361-56-2.png)
(E)-5-((((4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)methyl)amino)methylene)-1-(p-tolyl)pyrimidine-2,4,6(1H,3H,5H)-trione
TL;DR: (E)-5-((((4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)methyl)amino)methylene)-1-(p-tolyl)pyrimidine-2,4,6(1H,3H,5H)-trione (CAS 384361-56-2) is a chemical compound with molecular formula C25H26N4O6 and molecular weight 478.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-hydroxy-5-[(4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)methyliminomethyl]-1-(4-methylphenyl)pyrimidine-2,4-dione
Also Known As: (E)-5-((((4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)methyl)amino)methylene)-1-(p-tolyl)pyrimidine-2,4,6(1H,3H,5H)-trione, (5E)-5-({[(4-methoxy-6-methyl-5,6,7,8-tetrahydro[1,3]dioxolo[4,5-g]isoquinolin-5-yl)methyl]amino}methylidene)-1-(4-methylphenyl)pyrimidine-2,4,6(1H,3H,5H)-trione, 5-[[(4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)methylamino]methylidene]-1-(4-methylphenyl)-1,3-diazinane-2,4,6-trione
| Molecular Formula | C25H26N4O6 |
|---|---|
| Molecular Weight | 478.19 g/mol |
| LogP | 1.92522 |
| Topological Polar Surface Area | 118.38 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 5 |
| Exact Mass | 478.18524 |
| Heavy Atoms | 35 |
| Complexity | 1423.8403 |
Chemical Identifiers
| CAS Number | 384361-56-2 |
|---|---|
| SMILES | CC1=CC=C(C=C1)N2C(=C(C(=O)NC2=O)C=NCC3C4=C(C5=C(C=C4CCN3C)OCO5)OC)O |
Product Overview
(E)-5-((((4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)methyl)amino)methylene)-1-(p-tolyl)pyrimidine-2,4,6(1H,3H,5H)-trione (CAS 384361-56-2), with molecular formula C25H26N4O6 and molecular weight 478.19 g/mol. IUPAC: 6-hydroxy-5-[(4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)methyliminomethyl]-1-(4-methylphenyl)pyrimidine-2,4-dione.
Chemical Property Profile of (E)-5-((((4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)methyl)amino)methylene)-1-(p-tolyl)pyrimidine-2,4,6(1H,3H,5H)-trione
Property Insights of (E)-5-((((4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)methyl)amino)methylene)-1-(p-tolyl)pyrimidine-2,4,6(1H,3H,5H)-trione
The XLogP value of 1.92522 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (E)-5-((((4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)methyl)amino)methylene)-1-(p-tolyl)pyrimidine-2,4,6(1H,3H,5H)-trione. The TPSA of 118.38 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-5-((((4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)methyl)amino)methylene)-1-(p-tolyl)pyrimidine-2,4,6(1H,3H,5H)-trione. Following Lipinski's Rule of Five, (E)-5-((((4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)methyl)amino)methylene)-1-(p-tolyl)pyrimidine-2,4,6(1H,3H,5H)-trione has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-5-((((4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)methyl)amino)methylene)-1-(p-tolyl)pyrimidine-2,4,6(1H,3H,5H)-trione?
The CAS number of (E)-5-((((4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)methyl)amino)methylene)-1-(p-tolyl)pyrimidine-2,4,6(1H,3H,5H)-trione is 384361-56-2.
What is the molecular formula of (E)-5-((((4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)methyl)amino)methylene)-1-(p-tolyl)pyrimidine-2,4,6(1H,3H,5H)-trione?
The molecular formula of (E)-5-((((4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)methyl)amino)methylene)-1-(p-tolyl)pyrimidine-2,4,6(1H,3H,5H)-trione is C25H26N4O6.
What is the molecular weight of (E)-5-((((4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)methyl)amino)methylene)-1-(p-tolyl)pyrimidine-2,4,6(1H,3H,5H)-trione?
The molecular weight of (E)-5-((((4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)methyl)amino)methylene)-1-(p-tolyl)pyrimidine-2,4,6(1H,3H,5H)-trione is 478.19 g/mol.
Where can I buy (E)-5-((((4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)methyl)amino)methylene)-1-(p-tolyl)pyrimidine-2,4,6(1H,3H,5H)-trione?
You can request a quote for (E)-5-((((4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)methyl)amino)methylene)-1-(p-tolyl)pyrimidine-2,4,6(1H,3H,5H)-trione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-5-((((4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)methyl)amino)methylene)-1-(p-tolyl)pyrimidine-2,4,6(1H,3H,5H)-trione?
Yes, KEHONG BIO provides custom synthesis services for (E)-5-((((4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)methyl)amino)methylene)-1-(p-tolyl)pyrimidine-2,4,6(1H,3H,5H)-trione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.