AF-399/41115293
TL;DR: AF-399/41115293 (CAS 384359-88-0) is a chemical compound with molecular formula C23H20N2O3S and molecular weight 404.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4E)-4-[hydroxy(phenyl)methylidene]-5-(4-propan-2-ylphenyl)-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione
Also Known As: AF-399/41115293, 4-benzoyl-3-hydroxy-5-(4-isopropylphenyl)-1-(1,3-thiazol-2-yl)-1,5-dihydro-2H-pyrrol-2-one, (4E)-4-[hydroxy(phenyl)methylidene]-5-(4-propan-2-ylphenyl)-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione, 4-benzoyl-3-hydroxy-5-(4-isopropylphenyl)-1-(thiazol-2-yl)-1H-pyrrol-2(5H)-one, 3-hydroxy-4-(phenylcarbonyl)-5-[4-(propan-2-yl)phenyl]-1-(1,3-thiazol-2-yl)-1,5-dihydro-2H-pyrrol-2-one
| Molecular Formula | C23H20N2O3S |
|---|---|
| Molecular Weight | 404.12 g/mol |
| LogP | 4.8928 |
| Topological Polar Surface Area | 70.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 404.11948 |
| Heavy Atoms | 29 |
| Complexity | 1071.0803 |
Chemical Identifiers
| CAS Number | 384359-88-0 |
|---|---|
| SMILES | CC(C)C1=CC=C(C=C1)C2/C(=C(/C3=CC=CC=C3)\O)/C(=O)C(=O)N2C4=NC=CS4 |
Product Overview
AF-399/41115293 (CAS 384359-88-0), with molecular formula C23H20N2O3S and molecular weight 404.12 g/mol. IUPAC: (4E)-4-[hydroxy(phenyl)methylidene]-5-(4-propan-2-ylphenyl)-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione.
Chemical Property Profile of AF-399/41115293
Property Insights of AF-399/41115293
The XLogP value of 4.8928 indicates that AF-399/41115293 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 70.5 Ų falls within the moderate polarity range, balancing permeability and solubility for AF-399/41115293. Following Lipinski's Rule of Five, AF-399/41115293 has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AF-399/41115293?
The CAS number of AF-399/41115293 is 384359-88-0.
What is the molecular formula of AF-399/41115293?
The molecular formula of AF-399/41115293 is C23H20N2O3S.
What is the molecular weight of AF-399/41115293?
The molecular weight of AF-399/41115293 is 404.12 g/mol.
Where can I buy AF-399/41115293?
You can request a quote for AF-399/41115293 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AF-399/41115293?
Yes, KEHONG BIO provides custom synthesis services for AF-399/41115293 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.