GANAXOLONE
TL;DR: GANAXOLONE (CAS 38398-32-2) is a chemical compound with molecular formula C22H36O2 and molecular weight 332.27 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(3R,5S,10S,13S,17S)-3-hydroxy-3,10,13-trimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]ethanone
Also Known As: Ganaxolone [USAN], Ganaxolone [USAN:INN], CCD 1042, 3alpha-Hydroxy-3beta-methyl-5alpha-pregnan-20-one, (3alpha,5alpha)-3-Hydroxy-3-methylpregnan-20-one
| Molecular Formula | C22H36O2 |
|---|---|
| Molecular Weight | 332.27 g/mol |
| LogP | 5.0 |
| Topological Polar Surface Area | 37.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 332.27155 |
| Heavy Atoms | 24 |
| Complexity | 542.0 |
Chemical Identifiers
| CAS Number | 38398-32-2 |
|---|---|
| SMILES | CC(=O)[C@H]1CCC2[C@@]1(CCC3C2CC[C@@H]4[C@@]3(CC[C@@](C4)(C)O)C)C |
| InChIKey | PGTVWKLGGCQMBR-XYZZJYPZSA-N |
Product Overview
GANAXOLONE (CAS 38398-32-2), with molecular formula C22H36O2 and molecular weight 332.27 g/mol. IUPAC: 1-[(3R,5S,10S,13S,17S)-3-hydroxy-3,10,13-trimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]ethanone.
Chemical Property Profile of GANAXOLONE
Property Insights of GANAXOLONE
The XLogP value of 5.0 indicates that GANAXOLONE is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 37.3 Ų, GANAXOLONE exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, GANAXOLONE has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of GANAXOLONE?
The CAS number of GANAXOLONE is 38398-32-2.
What is the molecular formula of GANAXOLONE?
The molecular formula of GANAXOLONE is C22H36O2.
What is the molecular weight of GANAXOLONE?
The molecular weight of GANAXOLONE is 332.27 g/mol.
Where can I buy GANAXOLONE?
You can request a quote for GANAXOLONE directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for GANAXOLONE?
Yes, KEHONG BIO provides custom synthesis services for GANAXOLONE and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.