Histidylprolineamide structure

Histidylprolineamide

TL;DR: Histidylprolineamide (CAS 38370-89-7) is a chemical compound with molecular formula C11H17N5O2 and molecular weight 251.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2S)-1-[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carboxamide

Also Known As: Histidylprolineamide, His-pro-amide, l-histidyl-l-prolinamide, Taltirelin Impurity 2, histidyl-proline amide

CAS: 38370-89-7
Molecular Formula C11H17N5O2
Molecular Weight 251.14 g/mol
LogP -2.2
Topological Polar Surface Area 118.0 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 4
Rotatable Bonds 4
Exact Mass 251.13823
Heavy Atoms 18
Complexity 335.0

Chemical Identifiers

CAS Number 38370-89-7
SMILES C1C[C@H](N(C1)C(=O)[C@H](CC2=CN=CN2)N)C(=O)N
InChIKey BVQMQRWLLWQCLL-IUCAKERBSA-N

Patent-Derived Application Labels

Derived from 4 IPC patent classification(s) across the SureChEMBL global patent database.

Heterocyclic Building Blocks (22 patents) Organic Building Blocks (3 patents) Peptides & Amino Acids (26 patents) Pharmaceutical Intermediates (49 patents)

Product Overview

Histidylprolineamide (CAS 38370-89-7), with molecular formula C11H17N5O2 and molecular weight 251.14 g/mol. IUPAC: (2S)-1-[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Histidylprolineamide

XLogP
-2.2
TPSA (Topological Polar Surface Area)
118.0
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
4
Rotatable Bonds
4
Heavy Atoms
18
Complexity
335.0
Exact Mass
251.13823
Monoisotopic Mass
251.13823
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Histidylprolineamide

The XLogP value of -2.2 indicates that Histidylprolineamide is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 118.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Histidylprolineamide. Following Lipinski's Rule of Five, Histidylprolineamide has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Histidylprolineamide?

The CAS number of Histidylprolineamide is 38370-89-7.

What is the molecular formula of Histidylprolineamide?

The molecular formula of Histidylprolineamide is C11H17N5O2.

What is the molecular weight of Histidylprolineamide?

The molecular weight of Histidylprolineamide is 251.14 g/mol.

Where can I buy Histidylprolineamide?

You can request a quote for Histidylprolineamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Histidylprolineamide?

Yes, KEHONG BIO provides custom synthesis services for Histidylprolineamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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