(Z)-N-(3-oxo-1-(thiophen-2-yl)-3-((3-(trifluoromethyl)phenyl)amino)prop-1-en-2-yl)furan-2-carboxamide
TL;DR: (Z)-N-(3-oxo-1-(thiophen-2-yl)-3-((3-(trifluoromethyl)phenyl)amino)prop-1-en-2-yl)furan-2-carboxamide (CAS 383372-29-0) is a chemical compound with molecular formula C19H13F3N2O3S and molecular weight 406.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(Z)-3-oxo-1-thiophen-2-yl-3-[3-(trifluoromethyl)anilino]prop-1-en-2-yl]furan-2-carboxamide
Also Known As: (Z)-N-(3-oxo-1-(thiophen-2-yl)-3-((3-(trifluoromethyl)phenyl)amino)prop-1-en-2-yl)furan-2-carboxamide, N-[(1Z)-3-oxo-1-(thiophen-2-yl)-3-{[3-(trifluoromethyl)phenyl]amino}prop-1-en-2-yl]furan-2-carboxamide, N-[(Z)-3-oxo-1-thiophen-2-yl-3-[3-(trifluoromethyl)anilino]prop-1-en-2-yl]furan-2-carboxamide
| Molecular Formula | C19H13F3N2O3S |
|---|---|
| Molecular Weight | 406.06 g/mol |
| LogP | 4.7695 |
| Topological Polar Surface Area | 71.34 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 406.0599 |
| Heavy Atoms | 28 |
| Complexity | 993.8677 |
Chemical Identifiers
| CAS Number | 383372-29-0 |
|---|---|
| SMILES | C1=CC(=CC(=C1)NC(=O)/C(=C/C2=CC=CS2)/NC(=O)C3=CC=CO3)C(F)(F)F |
Product Overview
(Z)-N-(3-oxo-1-(thiophen-2-yl)-3-((3-(trifluoromethyl)phenyl)amino)prop-1-en-2-yl)furan-2-carboxamide (CAS 383372-29-0), with molecular formula C19H13F3N2O3S and molecular weight 406.06 g/mol. IUPAC: N-[(Z)-3-oxo-1-thiophen-2-yl-3-[3-(trifluoromethyl)anilino]prop-1-en-2-yl]furan-2-carboxamide.
Chemical Property Profile of (Z)-N-(3-oxo-1-(thiophen-2-yl)-3-((3-(trifluoromethyl)phenyl)amino)prop-1-en-2-yl)furan-2-carboxamide
Property Insights of (Z)-N-(3-oxo-1-(thiophen-2-yl)-3-((3-(trifluoromethyl)phenyl)amino)prop-1-en-2-yl)furan-2-carboxamide
The XLogP value of 4.7695 indicates that (Z)-N-(3-oxo-1-(thiophen-2-yl)-3-((3-(trifluoromethyl)phenyl)amino)prop-1-en-2-yl)furan-2-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 71.34 Ų falls within the moderate polarity range, balancing permeability and solubility for (Z)-N-(3-oxo-1-(thiophen-2-yl)-3-((3-(trifluoromethyl)phenyl)amino)prop-1-en-2-yl)furan-2-carboxamide. Following Lipinski's Rule of Five, (Z)-N-(3-oxo-1-(thiophen-2-yl)-3-((3-(trifluoromethyl)phenyl)amino)prop-1-en-2-yl)furan-2-carboxamide has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (Z)-N-(3-oxo-1-(thiophen-2-yl)-3-((3-(trifluoromethyl)phenyl)amino)prop-1-en-2-yl)furan-2-carboxamide?
The CAS number of (Z)-N-(3-oxo-1-(thiophen-2-yl)-3-((3-(trifluoromethyl)phenyl)amino)prop-1-en-2-yl)furan-2-carboxamide is 383372-29-0.
What is the molecular formula of (Z)-N-(3-oxo-1-(thiophen-2-yl)-3-((3-(trifluoromethyl)phenyl)amino)prop-1-en-2-yl)furan-2-carboxamide?
The molecular formula of (Z)-N-(3-oxo-1-(thiophen-2-yl)-3-((3-(trifluoromethyl)phenyl)amino)prop-1-en-2-yl)furan-2-carboxamide is C19H13F3N2O3S.
What is the molecular weight of (Z)-N-(3-oxo-1-(thiophen-2-yl)-3-((3-(trifluoromethyl)phenyl)amino)prop-1-en-2-yl)furan-2-carboxamide?
The molecular weight of (Z)-N-(3-oxo-1-(thiophen-2-yl)-3-((3-(trifluoromethyl)phenyl)amino)prop-1-en-2-yl)furan-2-carboxamide is 406.06 g/mol.
Where can I buy (Z)-N-(3-oxo-1-(thiophen-2-yl)-3-((3-(trifluoromethyl)phenyl)amino)prop-1-en-2-yl)furan-2-carboxamide?
You can request a quote for (Z)-N-(3-oxo-1-(thiophen-2-yl)-3-((3-(trifluoromethyl)phenyl)amino)prop-1-en-2-yl)furan-2-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (Z)-N-(3-oxo-1-(thiophen-2-yl)-3-((3-(trifluoromethyl)phenyl)amino)prop-1-en-2-yl)furan-2-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for (Z)-N-(3-oxo-1-(thiophen-2-yl)-3-((3-(trifluoromethyl)phenyl)amino)prop-1-en-2-yl)furan-2-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.