![N-{(E)-[1-(1,3-thiazol-2-yl)-1H-pyrrol-2-yl]methylidene}[3-(trifluoromethyl)phenyl]methanamine structure](/static/products/3831/383147-59-9.webp)
N-{(E)-[1-(1,3-thiazol-2-yl)-1H-pyrrol-2-yl]methylidene}[3-(trifluoromethyl)phenyl]methanamine
TL;DR: N-{(E)-[1-(1,3-thiazol-2-yl)-1H-pyrrol-2-yl]methylidene}[3-(trifluoromethyl)phenyl]methanamine (CAS 383147-59-9) is a chemical compound with molecular formula C16H12F3N3S and molecular weight 335.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[1-(1,3-thiazol-2-yl)pyrrol-2-yl]-N-[[3-(trifluoromethyl)phenyl]methyl]methanimine
Also Known As: N-{(E)-[1-(1,3-thiazol-2-yl)-1H-pyrrol-2-yl]methylidene}[3-(trifluoromethyl)phenyl]methanamine, 12R-0630, {[1-(1,3-thiazol-2-yl)-1H-pyrrol-2-yl]methylidene}({[3-(trifluoromethyl)phenyl]methyl})amine, 1-[1-(1,3-thiazol-2-yl)pyrrol-2-yl]-N-[[3-(trifluoromethyl)phenyl]methyl]methanimine, 1-[1-(1,3-Thiazol-2-yl)-1H-pyrrol-2-yl]-N-{[3-(trifluoromethyl)phenyl]methyl}methanimine
| Molecular Formula | C16H12F3N3S |
|---|---|
| Molecular Weight | 335.07 g/mol |
| LogP | 4.5717 |
| Topological Polar Surface Area | 30.18 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 335.0704 |
| Heavy Atoms | 23 |
| Complexity | 804.0972 |
Chemical Identifiers
| CAS Number | 383147-59-9 |
|---|---|
| SMILES | C1=CC(=CC(=C1)C(F)(F)F)CN=CC2=CC=CN2C3=NC=CS3 |
Product Overview
N-{(E)-[1-(1,3-thiazol-2-yl)-1H-pyrrol-2-yl]methylidene}[3-(trifluoromethyl)phenyl]methanamine (CAS 383147-59-9), with molecular formula C16H12F3N3S and molecular weight 335.07 g/mol. IUPAC: 1-[1-(1,3-thiazol-2-yl)pyrrol-2-yl]-N-[[3-(trifluoromethyl)phenyl]methyl]methanimine.
Chemical Property Profile of N-{(E)-[1-(1,3-thiazol-2-yl)-1H-pyrrol-2-yl]methylidene}[3-(trifluoromethyl)phenyl]methanamine
Property Insights of N-{(E)-[1-(1,3-thiazol-2-yl)-1H-pyrrol-2-yl]methylidene}[3-(trifluoromethyl)phenyl]methanamine
The XLogP value of 4.5717 indicates that N-{(E)-[1-(1,3-thiazol-2-yl)-1H-pyrrol-2-yl]methylidene}[3-(trifluoromethyl)phenyl]methanamine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 30.18 Ų, N-{(E)-[1-(1,3-thiazol-2-yl)-1H-pyrrol-2-yl]methylidene}[3-(trifluoromethyl)phenyl]methanamine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-{(E)-[1-(1,3-thiazol-2-yl)-1H-pyrrol-2-yl]methylidene}[3-(trifluoromethyl)phenyl]methanamine has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-{(E)-[1-(1,3-thiazol-2-yl)-1H-pyrrol-2-yl]methylidene}[3-(trifluoromethyl)phenyl]methanamine?
The CAS number of N-{(E)-[1-(1,3-thiazol-2-yl)-1H-pyrrol-2-yl]methylidene}[3-(trifluoromethyl)phenyl]methanamine is 383147-59-9.
What is the molecular formula of N-{(E)-[1-(1,3-thiazol-2-yl)-1H-pyrrol-2-yl]methylidene}[3-(trifluoromethyl)phenyl]methanamine?
The molecular formula of N-{(E)-[1-(1,3-thiazol-2-yl)-1H-pyrrol-2-yl]methylidene}[3-(trifluoromethyl)phenyl]methanamine is C16H12F3N3S.
What is the molecular weight of N-{(E)-[1-(1,3-thiazol-2-yl)-1H-pyrrol-2-yl]methylidene}[3-(trifluoromethyl)phenyl]methanamine?
The molecular weight of N-{(E)-[1-(1,3-thiazol-2-yl)-1H-pyrrol-2-yl]methylidene}[3-(trifluoromethyl)phenyl]methanamine is 335.07 g/mol.
Where can I buy N-{(E)-[1-(1,3-thiazol-2-yl)-1H-pyrrol-2-yl]methylidene}[3-(trifluoromethyl)phenyl]methanamine?
You can request a quote for N-{(E)-[1-(1,3-thiazol-2-yl)-1H-pyrrol-2-yl]methylidene}[3-(trifluoromethyl)phenyl]methanamine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-{(E)-[1-(1,3-thiazol-2-yl)-1H-pyrrol-2-yl]methylidene}[3-(trifluoromethyl)phenyl]methanamine?
Yes, KEHONG BIO provides custom synthesis services for N-{(E)-[1-(1,3-thiazol-2-yl)-1H-pyrrol-2-yl]methylidene}[3-(trifluoromethyl)phenyl]methanamine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.