(-)-(Trifluoromethyl)dihydrocinchonidine dihydrochloride structure

(-)-(Trifluoromethyl)dihydrocinchonidine dihydrochloride

TL;DR: (-)-(Trifluoromethyl)dihydrocinchonidine dihydrochloride (CAS 38199-25-6) is a chemical compound with molecular formula C20H25Cl2F3N2O and molecular weight 436.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(R)-[(2S,4R,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-[7-(trifluoromethyl)quinolin-4-yl]methanol;dihydrochloride

Also Known As: (-)-(Trifluoromethyl)dihydrocinchonidine dihydrochloride, Cinchonan-9-ol, 10,11-dihydro-7'-(trifluoromethyl)-, dihydrochloride, (8alpha,9R)-, (1xi,9R)-7'-(Trifluoromethyl)-3alpha,4beta,8alpha-10,11-dihydrocinchonan-9-ol--hydrogen chloride (1/2), (R)-[(2S,4R,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-[7-(trifluoromethyl)quinolin-4-yl]methanol dihydrochloride

CAS: 38199-25-6
Molecular Formula C20H25Cl2F3N2O
Molecular Weight 436.13 g/mol
LogP 5.251
Topological Polar Surface Area 36.4 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 6
Rotatable Bonds 3
Exact Mass 436.1296
Heavy Atoms 28
Complexity 500.0

Chemical Identifiers

CAS Number 38199-25-6
SMILES CC[C@H]1CN2CC[C@@H]1C[C@H]2[C@@H](C3=C4C=CC(=CC4=NC=C3)C(F)(F)F)O.Cl.Cl
InChIKey CWIQQRJJQPCRKM-LLNSMMKGSA-N

Product Overview

(-)-(Trifluoromethyl)dihydrocinchonidine dihydrochloride (CAS 38199-25-6), with molecular formula C20H25Cl2F3N2O and molecular weight 436.13 g/mol. IUPAC: (R)-[(2S,4R,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-[7-(trifluoromethyl)quinolin-4-yl]methanol;dihydrochloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of (-)-(Trifluoromethyl)dihydrocinchonidine dihydrochloride

XLogP
5.251
TPSA (Topological Polar Surface Area)
36.4
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
6
Rotatable Bonds
3
Heavy Atoms
28
Complexity
500.0
Exact Mass
436.1296
Monoisotopic Mass
436.1296
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of (-)-(Trifluoromethyl)dihydrocinchonidine dihydrochloride

The XLogP value of 5.251 indicates that (-)-(Trifluoromethyl)dihydrocinchonidine dihydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 36.4 Ų, (-)-(Trifluoromethyl)dihydrocinchonidine dihydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (-)-(Trifluoromethyl)dihydrocinchonidine dihydrochloride has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of (-)-(Trifluoromethyl)dihydrocinchonidine dihydrochloride?

The CAS number of (-)-(Trifluoromethyl)dihydrocinchonidine dihydrochloride is 38199-25-6.

What is the molecular formula of (-)-(Trifluoromethyl)dihydrocinchonidine dihydrochloride?

The molecular formula of (-)-(Trifluoromethyl)dihydrocinchonidine dihydrochloride is C20H25Cl2F3N2O.

What is the molecular weight of (-)-(Trifluoromethyl)dihydrocinchonidine dihydrochloride?

The molecular weight of (-)-(Trifluoromethyl)dihydrocinchonidine dihydrochloride is 436.13 g/mol.

Where can I buy (-)-(Trifluoromethyl)dihydrocinchonidine dihydrochloride?

You can request a quote for (-)-(Trifluoromethyl)dihydrocinchonidine dihydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for (-)-(Trifluoromethyl)dihydrocinchonidine dihydrochloride?

Yes, KEHONG BIO provides custom synthesis services for (-)-(Trifluoromethyl)dihydrocinchonidine dihydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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