4-(4-Ethoxybenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1,5-dihydro-2h-pyrrol-2-one
TL;DR: 4-(4-Ethoxybenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1,5-dihydro-2h-pyrrol-2-one (CAS 381702-30-3) is a chemical compound with molecular formula C22H17FN2O4S and molecular weight 424.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-[(4-ethoxyphenyl)-hydroxymethylidene]-5-(4-fluorophenyl)-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione
Also Known As: 4-(4-Ethoxybenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1,5-dihydro-2h-pyrrol-2-one, 4-(4-Ethoxybenzoyl)-5-(4-fluorophenyl)-1,5-dihydro-3-hydroxy-1-(2-thiazolyl)-2H-pyrrol-2-one, 4-[(4-ethoxyphenyl)-hydroxymethylidene]-5-(4-fluorophenyl)-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione
| Molecular Formula | C22H17FN2O4S |
|---|---|
| Molecular Weight | 424.09 g/mol |
| LogP | 4.3072 |
| Topological Polar Surface Area | 79.73 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 424.0893 |
| Heavy Atoms | 30 |
| Complexity | 1109.054 |
Chemical Identifiers
| CAS Number | 381702-30-3 |
|---|---|
| SMILES | CCOC1=CC=C(C=C1)C(=C2C(N(C(=O)C2=O)C3=NC=CS3)C4=CC=C(C=C4)F)O |
Product Overview
4-(4-Ethoxybenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1,5-dihydro-2h-pyrrol-2-one (CAS 381702-30-3), with molecular formula C22H17FN2O4S and molecular weight 424.09 g/mol. IUPAC: 4-[(4-ethoxyphenyl)-hydroxymethylidene]-5-(4-fluorophenyl)-1-(1,3-thiazol-2-yl)pyrrolidine-2,3-dione.
Chemical Property Profile of 4-(4-Ethoxybenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1,5-dihydro-2h-pyrrol-2-one
Property Insights of 4-(4-Ethoxybenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1,5-dihydro-2h-pyrrol-2-one
The XLogP value of 4.3072 indicates that 4-(4-Ethoxybenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1,5-dihydro-2h-pyrrol-2-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 79.73 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-(4-Ethoxybenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1,5-dihydro-2h-pyrrol-2-one. Following Lipinski's Rule of Five, 4-(4-Ethoxybenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1,5-dihydro-2h-pyrrol-2-one has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(4-Ethoxybenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1,5-dihydro-2h-pyrrol-2-one?
The CAS number of 4-(4-Ethoxybenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1,5-dihydro-2h-pyrrol-2-one is 381702-30-3.
What is the molecular formula of 4-(4-Ethoxybenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1,5-dihydro-2h-pyrrol-2-one?
The molecular formula of 4-(4-Ethoxybenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1,5-dihydro-2h-pyrrol-2-one is C22H17FN2O4S.
What is the molecular weight of 4-(4-Ethoxybenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1,5-dihydro-2h-pyrrol-2-one?
The molecular weight of 4-(4-Ethoxybenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1,5-dihydro-2h-pyrrol-2-one is 424.09 g/mol.
Where can I buy 4-(4-Ethoxybenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1,5-dihydro-2h-pyrrol-2-one?
You can request a quote for 4-(4-Ethoxybenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1,5-dihydro-2h-pyrrol-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(4-Ethoxybenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1,5-dihydro-2h-pyrrol-2-one?
Yes, KEHONG BIO provides custom synthesis services for 4-(4-Ethoxybenzoyl)-5-(4-fluorophenyl)-3-hydroxy-1-(thiazol-2-yl)-1,5-dihydro-2h-pyrrol-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.