(E)-1-(benzimidazol-1-yl)-3-thiophen-2-ylprop-2-en-1-one
TL;DR: (E)-1-(benzimidazol-1-yl)-3-thiophen-2-ylprop-2-en-1-one (CAS 381684-99-7) is a chemical compound with molecular formula C14H10N2OS and molecular weight 254.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-1-(benzimidazol-1-yl)-3-thiophen-2-ylprop-2-en-1-one
Also Known As: (E)-1-(benzimidazol-1-yl)-3-thiophen-2-ylprop-2-en-1-one, (2E)-1-benzimidazolyl-3-(2-thienyl)prop-2-en-1-one, (2E)-1-(1H-benzimidazol-1-yl)-3-(thiophen-2-yl)prop-2-en-1-one, (E)-1-(1H-benzo[d]imidazol-1-yl)-3-(thiophen-2-yl)prop-2-en-1-one
| Molecular Formula | C14H10N2OS |
|---|---|
| Molecular Weight | 254.05 g/mol |
| LogP | 3.4514 |
| Topological Polar Surface Area | 34.89 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 254.05139 |
| Heavy Atoms | 18 |
| Complexity | 710.31616 |
Chemical Identifiers
| CAS Number | 381684-99-7 |
|---|---|
| SMILES | C1=CC=C2C(=C1)N=CN2C(=O)/C=C/C3=CC=CS3 |
Product Overview
(E)-1-(benzimidazol-1-yl)-3-thiophen-2-ylprop-2-en-1-one (CAS 381684-99-7), with molecular formula C14H10N2OS and molecular weight 254.05 g/mol. IUPAC: (E)-1-(benzimidazol-1-yl)-3-thiophen-2-ylprop-2-en-1-one.
Chemical Property Profile of (E)-1-(benzimidazol-1-yl)-3-thiophen-2-ylprop-2-en-1-one
Property Insights of (E)-1-(benzimidazol-1-yl)-3-thiophen-2-ylprop-2-en-1-one
The XLogP value of 3.4514 indicates that (E)-1-(benzimidazol-1-yl)-3-thiophen-2-ylprop-2-en-1-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 34.89 Ų, (E)-1-(benzimidazol-1-yl)-3-thiophen-2-ylprop-2-en-1-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-1-(benzimidazol-1-yl)-3-thiophen-2-ylprop-2-en-1-one has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-1-(benzimidazol-1-yl)-3-thiophen-2-ylprop-2-en-1-one?
The CAS number of (E)-1-(benzimidazol-1-yl)-3-thiophen-2-ylprop-2-en-1-one is 381684-99-7.
What is the molecular formula of (E)-1-(benzimidazol-1-yl)-3-thiophen-2-ylprop-2-en-1-one?
The molecular formula of (E)-1-(benzimidazol-1-yl)-3-thiophen-2-ylprop-2-en-1-one is C14H10N2OS.
What is the molecular weight of (E)-1-(benzimidazol-1-yl)-3-thiophen-2-ylprop-2-en-1-one?
The molecular weight of (E)-1-(benzimidazol-1-yl)-3-thiophen-2-ylprop-2-en-1-one is 254.05 g/mol.
Where can I buy (E)-1-(benzimidazol-1-yl)-3-thiophen-2-ylprop-2-en-1-one?
You can request a quote for (E)-1-(benzimidazol-1-yl)-3-thiophen-2-ylprop-2-en-1-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-1-(benzimidazol-1-yl)-3-thiophen-2-ylprop-2-en-1-one?
Yes, KEHONG BIO provides custom synthesis services for (E)-1-(benzimidazol-1-yl)-3-thiophen-2-ylprop-2-en-1-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.