(E)-1-(4-benzylpiperazin-1-yl)-3-thiophen-2-ylprop-2-en-1-one
TL;DR: (E)-1-(4-benzylpiperazin-1-yl)-3-thiophen-2-ylprop-2-en-1-one (CAS 381683-86-9) is a chemical compound with molecular formula C18H20N2OS and molecular weight 312.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-1-(4-benzylpiperazin-1-yl)-3-thiophen-2-ylprop-2-en-1-one
Also Known As: BIM-0038233.P001, (E)-1-(4-benzylpiperazin-1-yl)-3-thiophen-2-ylprop-2-en-1-one, (2E)-1-[4-benzylpiperazinyl]-3-(2-thienyl)prop-2-en-1-one, (E)-1-(4-benzylpiperazin-1-yl)-3-(thiophen-2-yl)prop-2-en-1-one, (2E)-1-(4-benzylpiperazin-1-yl)-3-(thiophen-2-yl)prop-2-en-1-one
| Molecular Formula | C18H20N2OS |
|---|---|
| Molecular Weight | 312.13 g/mol |
| LogP | 3.1057 |
| Topological Polar Surface Area | 23.55 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 312.12964 |
| Heavy Atoms | 22 |
| Complexity | 613.8014 |
Chemical Identifiers
| CAS Number | 381683-86-9 |
|---|---|
| SMILES | C1CN(CCN1CC2=CC=CC=C2)C(=O)/C=C/C3=CC=CS3 |
Product Overview
(E)-1-(4-benzylpiperazin-1-yl)-3-thiophen-2-ylprop-2-en-1-one (CAS 381683-86-9), with molecular formula C18H20N2OS and molecular weight 312.13 g/mol. IUPAC: (E)-1-(4-benzylpiperazin-1-yl)-3-thiophen-2-ylprop-2-en-1-one.
Chemical Property Profile of (E)-1-(4-benzylpiperazin-1-yl)-3-thiophen-2-ylprop-2-en-1-one
Property Insights of (E)-1-(4-benzylpiperazin-1-yl)-3-thiophen-2-ylprop-2-en-1-one
The XLogP value of 3.1057 indicates that (E)-1-(4-benzylpiperazin-1-yl)-3-thiophen-2-ylprop-2-en-1-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 23.55 Ų, (E)-1-(4-benzylpiperazin-1-yl)-3-thiophen-2-ylprop-2-en-1-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-1-(4-benzylpiperazin-1-yl)-3-thiophen-2-ylprop-2-en-1-one has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-1-(4-benzylpiperazin-1-yl)-3-thiophen-2-ylprop-2-en-1-one?
The CAS number of (E)-1-(4-benzylpiperazin-1-yl)-3-thiophen-2-ylprop-2-en-1-one is 381683-86-9.
What is the molecular formula of (E)-1-(4-benzylpiperazin-1-yl)-3-thiophen-2-ylprop-2-en-1-one?
The molecular formula of (E)-1-(4-benzylpiperazin-1-yl)-3-thiophen-2-ylprop-2-en-1-one is C18H20N2OS.
What is the molecular weight of (E)-1-(4-benzylpiperazin-1-yl)-3-thiophen-2-ylprop-2-en-1-one?
The molecular weight of (E)-1-(4-benzylpiperazin-1-yl)-3-thiophen-2-ylprop-2-en-1-one is 312.13 g/mol.
Where can I buy (E)-1-(4-benzylpiperazin-1-yl)-3-thiophen-2-ylprop-2-en-1-one?
You can request a quote for (E)-1-(4-benzylpiperazin-1-yl)-3-thiophen-2-ylprop-2-en-1-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-1-(4-benzylpiperazin-1-yl)-3-thiophen-2-ylprop-2-en-1-one?
Yes, KEHONG BIO provides custom synthesis services for (E)-1-(4-benzylpiperazin-1-yl)-3-thiophen-2-ylprop-2-en-1-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.