![4-(Piperazin-1-ylcarbonyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one structure](/static/products/3816/38160-07-5.webp)
4-(Piperazin-1-ylcarbonyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one
TL;DR: 4-(Piperazin-1-ylcarbonyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one (CAS 38160-07-5) is a chemical compound with molecular formula C16H18F3N3O2 and molecular weight 341.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(piperazine-1-carbonyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one
Also Known As: AB01269433-02, 4-(piperazine-1-carbonyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one, 2-pyrrolidinone, 4-(1-piperazinylcarbonyl)-1-[3-(trifluoromethyl)phenyl]-, 4-(piperazin-1-ylcarbonyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one, 4-(Piperazine-1-carbonyl)-1-(3-trifluoromethyl-phenyl)-pyrrolidin-2-one
| Molecular Formula | C16H18F3N3O2 |
|---|---|
| Molecular Weight | 341.14 g/mol |
| LogP | 0.7 |
| Topological Polar Surface Area | 52.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 341.1351 |
| Heavy Atoms | 24 |
| Complexity | 491.0 |
Chemical Identifiers
| CAS Number | 38160-07-5 |
|---|---|
| SMILES | C1CN(CCN1)C(=O)C2CC(=O)N(C2)C3=CC=CC(=C3)C(F)(F)F |
| InChIKey | VVQDUCZKZVTNHG-UHFFFAOYSA-N |
Product Overview
4-(Piperazin-1-ylcarbonyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one (CAS 38160-07-5), with molecular formula C16H18F3N3O2 and molecular weight 341.14 g/mol. IUPAC: 4-(piperazine-1-carbonyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one.
Chemical Property Profile of 4-(Piperazin-1-ylcarbonyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one
Property Insights of 4-(Piperazin-1-ylcarbonyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one
The XLogP value of 0.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 4-(Piperazin-1-ylcarbonyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one. With a topological polar surface area (TPSA) of 52.7 Ų, 4-(Piperazin-1-ylcarbonyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-(Piperazin-1-ylcarbonyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(Piperazin-1-ylcarbonyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one?
The CAS number of 4-(Piperazin-1-ylcarbonyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one is 38160-07-5.
What is the molecular formula of 4-(Piperazin-1-ylcarbonyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one?
The molecular formula of 4-(Piperazin-1-ylcarbonyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one is C16H18F3N3O2.
What is the molecular weight of 4-(Piperazin-1-ylcarbonyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one?
The molecular weight of 4-(Piperazin-1-ylcarbonyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one is 341.14 g/mol.
Where can I buy 4-(Piperazin-1-ylcarbonyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one?
You can request a quote for 4-(Piperazin-1-ylcarbonyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(Piperazin-1-ylcarbonyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one?
Yes, KEHONG BIO provides custom synthesis services for 4-(Piperazin-1-ylcarbonyl)-1-[3-(trifluoromethyl)phenyl]pyrrolidin-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.