![methyl 2-[[(E)-3-(1,3-diphenylpyrazol-4-yl)prop-2-enoyl]amino]-4-methyl-1,3-thiazole-5-carboxylate structure](/static/products/3812/381202-90-0.webp)
methyl 2-[[(E)-3-(1,3-diphenylpyrazol-4-yl)prop-2-enoyl]amino]-4-methyl-1,3-thiazole-5-carboxylate
TL;DR: methyl 2-[[(E)-3-(1,3-diphenylpyrazol-4-yl)prop-2-enoyl]amino]-4-methyl-1,3-thiazole-5-carboxylate (CAS 381202-90-0) is a chemical compound with molecular formula C24H20N4O3S and molecular weight 444.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
methyl 2-[[(E)-3-(1,3-diphenylpyrazol-4-yl)prop-2-enoyl]amino]-4-methyl-1,3-thiazole-5-carboxylate
Also Known As: methyl 2-[[(E)-3-(1,3-diphenylpyrazol-4-yl)prop-2-enoyl]amino]-4-methyl-1,3-thiazole-5-carboxylate, (E)-methyl 2-(3-(1,3-diphenyl-1H-pyrazol-4-yl)acrylamido)-4-methylthiazole-5-carboxylate, methyl (2Z)-2-{[(2E)-3-(1,3-diphenyl-1H-pyrazol-4-yl)prop-2-enoyl]imino}-4-methyl-2,3-dihydro-1,3-thiazole-5-carboxylate, Methyl 2-[3-(1,3-diphenylpyrazol-4-yl)prop-2-enoylamino]-4-methyl-1,3-thiazole-5-carboxylate, methyl 2-{[(2E)-3-(1,3-diphenyl-1H-pyrazol-4-yl)prop-2-enoyl]amino}-4-methyl-1,3-thiazole-5-carboxylate
| Molecular Formula | C24H20N4O3S |
|---|---|
| Molecular Weight | 444.13 g/mol |
| LogP | 4.74272 |
| Topological Polar Surface Area | 86.11 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 444.1256 |
| Heavy Atoms | 32 |
| Complexity | 1277.3389 |
Chemical Identifiers
| CAS Number | 381202-90-0 |
|---|---|
| SMILES | CC1=C(SC(=N1)NC(=O)/C=C/C2=CN(N=C2C3=CC=CC=C3)C4=CC=CC=C4)C(=O)OC |
Product Overview
methyl 2-[[(E)-3-(1,3-diphenylpyrazol-4-yl)prop-2-enoyl]amino]-4-methyl-1,3-thiazole-5-carboxylate (CAS 381202-90-0), with molecular formula C24H20N4O3S and molecular weight 444.13 g/mol. IUPAC: methyl 2-[[(E)-3-(1,3-diphenylpyrazol-4-yl)prop-2-enoyl]amino]-4-methyl-1,3-thiazole-5-carboxylate.
Chemical Property Profile of methyl 2-[[(E)-3-(1,3-diphenylpyrazol-4-yl)prop-2-enoyl]amino]-4-methyl-1,3-thiazole-5-carboxylate
Property Insights of methyl 2-[[(E)-3-(1,3-diphenylpyrazol-4-yl)prop-2-enoyl]amino]-4-methyl-1,3-thiazole-5-carboxylate
The XLogP value of 4.74272 indicates that methyl 2-[[(E)-3-(1,3-diphenylpyrazol-4-yl)prop-2-enoyl]amino]-4-methyl-1,3-thiazole-5-carboxylate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 86.11 Ų falls within the moderate polarity range, balancing permeability and solubility for methyl 2-[[(E)-3-(1,3-diphenylpyrazol-4-yl)prop-2-enoyl]amino]-4-methyl-1,3-thiazole-5-carboxylate. Following Lipinski's Rule of Five, methyl 2-[[(E)-3-(1,3-diphenylpyrazol-4-yl)prop-2-enoyl]amino]-4-methyl-1,3-thiazole-5-carboxylate has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of methyl 2-[[(E)-3-(1,3-diphenylpyrazol-4-yl)prop-2-enoyl]amino]-4-methyl-1,3-thiazole-5-carboxylate?
The CAS number of methyl 2-[[(E)-3-(1,3-diphenylpyrazol-4-yl)prop-2-enoyl]amino]-4-methyl-1,3-thiazole-5-carboxylate is 381202-90-0.
What is the molecular formula of methyl 2-[[(E)-3-(1,3-diphenylpyrazol-4-yl)prop-2-enoyl]amino]-4-methyl-1,3-thiazole-5-carboxylate?
The molecular formula of methyl 2-[[(E)-3-(1,3-diphenylpyrazol-4-yl)prop-2-enoyl]amino]-4-methyl-1,3-thiazole-5-carboxylate is C24H20N4O3S.
What is the molecular weight of methyl 2-[[(E)-3-(1,3-diphenylpyrazol-4-yl)prop-2-enoyl]amino]-4-methyl-1,3-thiazole-5-carboxylate?
The molecular weight of methyl 2-[[(E)-3-(1,3-diphenylpyrazol-4-yl)prop-2-enoyl]amino]-4-methyl-1,3-thiazole-5-carboxylate is 444.13 g/mol.
Where can I buy methyl 2-[[(E)-3-(1,3-diphenylpyrazol-4-yl)prop-2-enoyl]amino]-4-methyl-1,3-thiazole-5-carboxylate?
You can request a quote for methyl 2-[[(E)-3-(1,3-diphenylpyrazol-4-yl)prop-2-enoyl]amino]-4-methyl-1,3-thiazole-5-carboxylate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for methyl 2-[[(E)-3-(1,3-diphenylpyrazol-4-yl)prop-2-enoyl]amino]-4-methyl-1,3-thiazole-5-carboxylate?
Yes, KEHONG BIO provides custom synthesis services for methyl 2-[[(E)-3-(1,3-diphenylpyrazol-4-yl)prop-2-enoyl]amino]-4-methyl-1,3-thiazole-5-carboxylate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.