![(5E)-5-[(2-piperazin-1-ylethylamino)methylidene]-1-[3-(trifluoromethyl)phenyl]-1,3-diazinane-2,4,6-trione structure](/static/products/381/381199-22-0.png)
(5E)-5-[(2-piperazin-1-ylethylamino)methylidene]-1-[3-(trifluoromethyl)phenyl]-1,3-diazinane-2,4,6-trione
概要：(5E)-5-[(2-piperazin-1-ylethylamino)methylidene]-1-[3-(trifluoromethyl)phenyl]-1,3-diazinane-2,4,6-trione（CAS 381199-22-0）是一种化学化合物，分子式为C18H20F3N5O3，分子量为411.15 g/mol。河南科弘生物科技有限公司提供CRO/CDMO定制合成服务，支持克级到吨级规格。
6-hydroxy-5-(2-piperazin-1-ylethyliminomethyl)-1-[3-(trifluoromethyl)phenyl]pyrimidine-2,4-dione
又称：(5E)-5-[(2-piperazin-1-ylethylamino)methylidene]-1-[3-(trifluoromethyl)phenyl]-1,3-diazinane-2,4,6-trione, (5E)-6-hydroxy-5-({[2-(piperazin-1-yl)ethyl]amino}methylidene)-3-[3-(trifluoromethyl)phenyl]pyrimidine-2,4(3H,5H)-dione, (E)-5-(((2-(piperazin-1-yl)ethyl)amino)methylene)-1-(3-(trifluoromethyl)phenyl)pyrimidine-2,4,6(1H,3H,5H)-trione, 5-[(2-piperazin-1-ylethylamino)methylidene]-1-[3-(trifluoromethyl)phenyl]-1,3-diazinane-2,4,6-trione
| 分子式 | C18H20F3N5O3 |
|---|---|
| 分子量 | 411.15 g/mol |
| LogP | 0.5743 |
| 拓扑极性表面积 | 102.72 Ų |
| 氢键供体数 | 3 |
| 氢键受体数 | 6 |
| 可旋转键数 | 5 |
| 精确质量 | 411.15182 |
| 重原子数 | 29 |
| 复杂度 | 1007.02203 |
化学标识符
| CAS 编号 | 381199-22-0 |
|---|---|
| SMILES | C1CN(CCN1)CCN=CC2=C(N(C(=O)NC2=O)C3=CC=CC(=C3)C(F)(F)F)O |
产品概述
(5E)-5-[(2-piperazin-1-ylethylamino)methylidene]-1-[3-(trifluoromethyl)phenyl]-1,3-diazinane-2,4,6-trione（CAS 381199-22-0），分子式为C18H20F3N5O3，分子量为411.15 g/mol。IUPAC名：6-hydroxy-5-(2-piperazin-1-ylethyliminomethyl)-1-[3-(trifluoromethyl)phenyl]pyrimidine-2,4-dione。
(5E)-5-[(2-piperazin-1-ylethylamino)methylidene]-1-[3-(trifluoromethyl)phenyl]-1,3-diazinane-2,4,6-trione化学性质概览
属性洞察：(5E)-5-[(2-piperazin-1-ylethylamino)methylidene]-1-[3-(trifluoromethyl)phenyl]-1,3-diazinane-2,4,6-trione
(5E)-5-[(2-piperazin-1-ylethylamino)methylidene]-1-[3-(trifluoromethyl)phenyl]-1,3-diazinane-2,4,6-trione的XLogP值为0.5743，表明具有中等亲脂性，在水溶性和膜透过性之间取得平衡。 TPSA为102.72 Ų，处于中等极性范围，在透过性和溶解性之间取得平衡。 根据Lipinski五规则，(5E)-5-[(2-piperazin-1-ylethylamino)methylidene]-1-[3-(trifluoromethyl)phenyl]-1,3-diazinane-2,4,6-trione有3个氢键供体和6个氢键受体，均在类药范围内，提示具有较好的口服生物利用度潜力。
常见问题
常见问题
(5E)-5-[(2-piperazin-1-ylethylamino)methylidene]-1-[3-(trifluoromethyl)phenyl]-1,3-diazinane-2,4,6-trione的CAS号是多少？
(5E)-5-[(2-piperazin-1-ylethylamino)methylidene]-1-[3-(trifluoromethyl)phenyl]-1,3-diazinane-2,4,6-trione的CAS号为381199-22-0。
(5E)-5-[(2-piperazin-1-ylethylamino)methylidene]-1-[3-(trifluoromethyl)phenyl]-1,3-diazinane-2,4,6-trione的分子式是什么？
(5E)-5-[(2-piperazin-1-ylethylamino)methylidene]-1-[3-(trifluoromethyl)phenyl]-1,3-diazinane-2,4,6-trione的分子式为C18H20F3N5O3。
(5E)-5-[(2-piperazin-1-ylethylamino)methylidene]-1-[3-(trifluoromethyl)phenyl]-1,3-diazinane-2,4,6-trione的分子量是多少？
(5E)-5-[(2-piperazin-1-ylethylamino)methylidene]-1-[3-(trifluoromethyl)phenyl]-1,3-diazinane-2,4,6-trione的分子量为411.15 g/mol。
在哪里可以购买(5E)-5-[(2-piperazin-1-ylethylamino)methylidene]-1-[3-(trifluoromethyl)phenyl]-1,3-diazinane-2,4,6-trione？
您可以直接向科弘生物询价(5E)-5-[(2-piperazin-1-ylethylamino)methylidene]-1-[3-(trifluoromethyl)phenyl]-1,3-diazinane-2,4,6-trione。联系我们或发送邮件至info@kehongbio.com获取报价和库存信息。
科弘生物是否提供(5E)-5-[(2-piperazin-1-ylethylamino)methylidene]-1-[3-(trifluoromethyl)phenyl]-1,3-diazinane-2,4,6-trione的定制合成服务？
是的，科弘生物提供(5E)-5-[(2-piperazin-1-ylethylamino)methylidene]-1-[3-(trifluoromethyl)phenyl]-1,3-diazinane-2,4,6-trione及相关化合物的定制合成服务。请联系我们并告知您的具体需求，包括数量、纯度和交期。