2-(Trifluoromethyl)acrylic acid structure

2-(Trifluoromethyl)acrylic acid

TL;DR: 2-(Trifluoromethyl)acrylic acid (CAS 381-98-6) is a chemical compound with molecular formula C4H3F3O2 and molecular weight 140.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-(trifluoromethyl)prop-2-enoic acid

Also Known As: 2-(Trifluoromethyl)acrylic acid, 2-(Trifluoromethyl)propenoic acid, 2-(trifluoromethyl)prop-2-enoic acid, Butantrone, TFMAA

CAS: 381-98-6
Molecular Formula C4H3F3O2
Molecular Weight 140.01 g/mol
LogP 1.3
Topological Polar Surface Area 37.3 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 5
Rotatable Bonds 1
Exact Mass 140.00851
Heavy Atoms 9
Complexity 146.0

Chemical Identifiers

CAS Number 381-98-6
SMILES C=C(C(=O)O)C(F)(F)F
InChIKey VLSRKCIBHNJFHA-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 19 IPC patent classification(s) across the SureChEMBL global patent database.

Agrochemicals (11 patents) Analytical Reagents (53 patents) Biotechnology (15 patents) Catalysts (12 patents) Coatings & Adhesives (39 patents) +14 more

Product Overview

2-(Trifluoromethyl)acrylic acid (CAS 381-98-6), with molecular formula C4H3F3O2 and molecular weight 140.01 g/mol. IUPAC: 2-(trifluoromethyl)prop-2-enoic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of 2-(Trifluoromethyl)acrylic acid

XLogP
1.3
TPSA (Topological Polar Surface Area)
37.3
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
5
Rotatable Bonds
1
Heavy Atoms
9
Complexity
146.0
Exact Mass
140.00851
Monoisotopic Mass
140.00851
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 2-(Trifluoromethyl)acrylic acid

The XLogP value of 1.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-(Trifluoromethyl)acrylic acid. With a topological polar surface area (TPSA) of 37.3 Ų, 2-(Trifluoromethyl)acrylic acid exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(Trifluoromethyl)acrylic acid has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 2-(Trifluoromethyl)acrylic acid?

The CAS number of 2-(Trifluoromethyl)acrylic acid is 381-98-6.

What is the molecular formula of 2-(Trifluoromethyl)acrylic acid?

The molecular formula of 2-(Trifluoromethyl)acrylic acid is C4H3F3O2.

What is the molecular weight of 2-(Trifluoromethyl)acrylic acid?

The molecular weight of 2-(Trifluoromethyl)acrylic acid is 140.01 g/mol.

Where can I buy 2-(Trifluoromethyl)acrylic acid?

You can request a quote for 2-(Trifluoromethyl)acrylic acid directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 2-(Trifluoromethyl)acrylic acid?

Yes, KEHONG BIO provides custom synthesis services for 2-(Trifluoromethyl)acrylic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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