2,2-Difluoroacetyl chloride
TL;DR: 2,2-Difluoroacetyl chloride (CAS 381-72-6) is a chemical compound with molecular formula C2HClF2O and molecular weight 113.97 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2,2-difluoroacetyl chloride
Also Known As: 2,2-difluoroacetyl chloride, Difluoroacetyl chloride, difluoroacetylchloride, C2HClF2O, difluoroacetic acid chloride
| Molecular Formula | C2HClF2O |
|---|---|
| Molecular Weight | 113.97 g/mol |
| LogP | 1.0169 |
| Topological Polar Surface Area | 17.07 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 1 |
| Exact Mass | 113.9684 |
| Heavy Atoms | 6 |
| Complexity | 62.568424 |
Chemical Identifiers
| CAS Number | 381-72-6 |
|---|---|
| SMILES | C(C(=O)Cl)(F)F |
Product Overview
2,2-Difluoroacetyl chloride (CAS 381-72-6), with molecular formula C2HClF2O and molecular weight 113.97 g/mol. IUPAC: 2,2-difluoroacetyl chloride.
Chemical Property Profile of 2,2-Difluoroacetyl chloride
Property Insights of 2,2-Difluoroacetyl chloride
The XLogP value of 1.0169 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2,2-Difluoroacetyl chloride. With a topological polar surface area (TPSA) of 17.07 Ų, 2,2-Difluoroacetyl chloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2,2-Difluoroacetyl chloride has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2,2-Difluoroacetyl chloride?
The CAS number of 2,2-Difluoroacetyl chloride is 381-72-6.
What is the molecular formula of 2,2-Difluoroacetyl chloride?
The molecular formula of 2,2-Difluoroacetyl chloride is C2HClF2O.
What is the molecular weight of 2,2-Difluoroacetyl chloride?
The molecular weight of 2,2-Difluoroacetyl chloride is 113.97 g/mol.
Where can I buy 2,2-Difluoroacetyl chloride?
You can request a quote for 2,2-Difluoroacetyl chloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2,2-Difluoroacetyl chloride?
Yes, KEHONG BIO provides custom synthesis services for 2,2-Difluoroacetyl chloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.