N-Methyldesloratadine
TL;DR: N-Methyldesloratadine (CAS 38092-89-6) is a chemical compound with molecular formula C20H21ClN2 and molecular weight 324.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
13-chloro-2-(1-methylpiperidin-4-ylidene)-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaene
Also Known As: 8-Chloroazatadine, N-Methyldesloratadine, N-Methyl Desloratadine, Methyl loratadine, Loratadine EP Impurity G
| Molecular Formula | C20H21ClN2 |
|---|---|
| Molecular Weight | 324.14 g/mol |
| LogP | 4.2 |
| Topological Polar Surface Area | 16.1 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 324.1393 |
| Heavy Atoms | 23 |
| Complexity | 451.0 |
Chemical Identifiers
| CAS Number | 38092-89-6 |
|---|---|
| SMILES | CN1CCC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC1 |
| InChIKey | VLXSCTINYKDTKR-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
N-Methyldesloratadine (CAS 38092-89-6), with molecular formula C20H21ClN2 and molecular weight 324.14 g/mol. IUPAC: 13-chloro-2-(1-methylpiperidin-4-ylidene)-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaene.
Chemical Property Profile of N-Methyldesloratadine
Property Insights of N-Methyldesloratadine
The XLogP value of 4.2 indicates that N-Methyldesloratadine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 16.1 Ų, N-Methyldesloratadine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-Methyldesloratadine has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-Methyldesloratadine?
The CAS number of N-Methyldesloratadine is 38092-89-6.
What is the molecular formula of N-Methyldesloratadine?
The molecular formula of N-Methyldesloratadine is C20H21ClN2.
What is the molecular weight of N-Methyldesloratadine?
The molecular weight of N-Methyldesloratadine is 324.14 g/mol.
Where can I buy N-Methyldesloratadine?
You can request a quote for N-Methyldesloratadine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-Methyldesloratadine?
Yes, KEHONG BIO provides custom synthesis services for N-Methyldesloratadine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.