![2-[4-(4-Phenoxybenzoyl)piperazin-1-yl]pyrimidine structure](/static/products/3802/380211-05-2.webp)
2-[4-(4-Phenoxybenzoyl)piperazin-1-yl]pyrimidine
TL;DR: 2-[4-(4-Phenoxybenzoyl)piperazin-1-yl]pyrimidine (CAS 380211-05-2) is a chemical compound with molecular formula C21H20N4O2 and molecular weight 360.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4-phenoxyphenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone
Also Known As: 2-[4-(4-phenoxybenzoyl)piperazin-1-yl]pyrimidine, (4-phenoxyphenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone
| Molecular Formula | C21H20N4O2 |
|---|---|
| Molecular Weight | 360.16 g/mol |
| LogP | 3.2313 |
| Topological Polar Surface Area | 58.56 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 360.15863 |
| Heavy Atoms | 27 |
| Complexity | 877.07477 |
Chemical Identifiers
| CAS Number | 380211-05-2 |
|---|---|
| SMILES | C1CN(CCN1C2=NC=CC=N2)C(=O)C3=CC=C(C=C3)OC4=CC=CC=C4 |
Product Overview
2-[4-(4-Phenoxybenzoyl)piperazin-1-yl]pyrimidine (CAS 380211-05-2), with molecular formula C21H20N4O2 and molecular weight 360.16 g/mol. IUPAC: (4-phenoxyphenyl)-(4-pyrimidin-2-ylpiperazin-1-yl)methanone.
Chemical Property Profile of 2-[4-(4-Phenoxybenzoyl)piperazin-1-yl]pyrimidine
Property Insights of 2-[4-(4-Phenoxybenzoyl)piperazin-1-yl]pyrimidine
The XLogP value of 3.2313 indicates that 2-[4-(4-Phenoxybenzoyl)piperazin-1-yl]pyrimidine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 58.56 Ų, 2-[4-(4-Phenoxybenzoyl)piperazin-1-yl]pyrimidine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-[4-(4-Phenoxybenzoyl)piperazin-1-yl]pyrimidine has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-[4-(4-Phenoxybenzoyl)piperazin-1-yl]pyrimidine?
The CAS number of 2-[4-(4-Phenoxybenzoyl)piperazin-1-yl]pyrimidine is 380211-05-2.
What is the molecular formula of 2-[4-(4-Phenoxybenzoyl)piperazin-1-yl]pyrimidine?
The molecular formula of 2-[4-(4-Phenoxybenzoyl)piperazin-1-yl]pyrimidine is C21H20N4O2.
What is the molecular weight of 2-[4-(4-Phenoxybenzoyl)piperazin-1-yl]pyrimidine?
The molecular weight of 2-[4-(4-Phenoxybenzoyl)piperazin-1-yl]pyrimidine is 360.16 g/mol.
Where can I buy 2-[4-(4-Phenoxybenzoyl)piperazin-1-yl]pyrimidine?
You can request a quote for 2-[4-(4-Phenoxybenzoyl)piperazin-1-yl]pyrimidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-[4-(4-Phenoxybenzoyl)piperazin-1-yl]pyrimidine?
Yes, KEHONG BIO provides custom synthesis services for 2-[4-(4-Phenoxybenzoyl)piperazin-1-yl]pyrimidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.