AF-399/15539140
TL;DR: AF-399/15539140 (CAS 379249-17-9) is a chemical compound with molecular formula C20H13F2N3O2S and molecular weight 397.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-[(E)-[4-(difluoromethoxy)phenyl]methylideneamino]-6-phenylthieno[2,3-d]pyrimidin-4-one
Also Known As: AF-399/15539140, 3-[(E)-[4-(difluoromethoxy)phenyl]methylideneamino]-6-phenylthieno[2,3-d]pyrimidin-4-one, 3-{[4-(difluoromethoxy)benzylidene]amino}-6-phenylthieno[2,3-d]pyrimidin-4(3H)-one, 3-{(1E)-2-[4-(difluoromethoxy)phenyl]-1-azavinyl}-6-phenyl-3-hydrothiopheno[2, 3-d]pyrimidin-4-one
| Molecular Formula | C20H13F2N3O2S |
|---|---|
| Molecular Weight | 397.07 g/mol |
| LogP | 4.6086 |
| Topological Polar Surface Area | 56.48 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 397.06964 |
| Heavy Atoms | 28 |
| Complexity | 1185.783 |
Chemical Identifiers
| CAS Number | 379249-17-9 |
|---|---|
| SMILES | C1=CC=C(C=C1)C2=CC3=C(S2)N=CN(C3=O)/N=C/C4=CC=C(C=C4)OC(F)F |
Product Overview
AF-399/15539140 (CAS 379249-17-9), with molecular formula C20H13F2N3O2S and molecular weight 397.07 g/mol. IUPAC: 3-[(E)-[4-(difluoromethoxy)phenyl]methylideneamino]-6-phenylthieno[2,3-d]pyrimidin-4-one.
Chemical Property Profile of AF-399/15539140
Property Insights of AF-399/15539140
The XLogP value of 4.6086 indicates that AF-399/15539140 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 56.48 Ų, AF-399/15539140 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, AF-399/15539140 has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AF-399/15539140?
The CAS number of AF-399/15539140 is 379249-17-9.
What is the molecular formula of AF-399/15539140?
The molecular formula of AF-399/15539140 is C20H13F2N3O2S.
What is the molecular weight of AF-399/15539140?
The molecular weight of AF-399/15539140 is 397.07 g/mol.
Where can I buy AF-399/15539140?
You can request a quote for AF-399/15539140 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AF-399/15539140?
Yes, KEHONG BIO provides custom synthesis services for AF-399/15539140 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.