![8-{[5-(4-Isopropylphenyl)thieno[2,3-d]pyrimidin-4-yl]oxy}-2-methylquinoline structure](/static/products/3792/379244-67-4.webp)
8-{[5-(4-Isopropylphenyl)thieno[2,3-d]pyrimidin-4-yl]oxy}-2-methylquinoline
TL;DR: 8-{[5-(4-Isopropylphenyl)thieno[2,3-d]pyrimidin-4-yl]oxy}-2-methylquinoline (CAS 379244-67-4) is a chemical compound with molecular formula C25H21N3OS and molecular weight 411.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(2-methylquinolin-8-yl)oxy-5-(4-propan-2-ylphenyl)thieno[2,3-d]pyrimidine
Also Known As: 8-{[5-(4-isopropylphenyl)thieno[2,3-d]pyrimidin-4-yl]oxy}-2-methylquinoline, AF-399/40684225, 4-(2-methylquinolin-8-yl)oxy-5-(4-propan-2-ylphenyl)thieno[2,3-d]pyrimidine, 2-methyl-8-({5-[4-(propan-2-yl)phenyl]thieno[2,3-d]pyrimidin-4-yl}oxy)quinoline, 4-(2-methyl(8-quinolyloxy))-5-[4-(methylethyl)phenyl]thiopheno[2,3-d]pyrimidin e
| Molecular Formula | C25H21N3OS |
|---|---|
| Molecular Weight | 411.14 g/mol |
| LogP | 7.13062 |
| Topological Polar Surface Area | 47.9 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 411.14053 |
| Heavy Atoms | 30 |
| Complexity | 1356.4855 |
Chemical Identifiers
| CAS Number | 379244-67-4 |
|---|---|
| SMILES | CC1=NC2=C(C=CC=C2OC3=C4C(=CSC4=NC=N3)C5=CC=C(C=C5)C(C)C)C=C1 |
Product Overview
8-{[5-(4-Isopropylphenyl)thieno[2,3-d]pyrimidin-4-yl]oxy}-2-methylquinoline (CAS 379244-67-4), with molecular formula C25H21N3OS and molecular weight 411.14 g/mol. IUPAC: 4-(2-methylquinolin-8-yl)oxy-5-(4-propan-2-ylphenyl)thieno[2,3-d]pyrimidine.
Chemical Property Profile of 8-{[5-(4-Isopropylphenyl)thieno[2,3-d]pyrimidin-4-yl]oxy}-2-methylquinoline
Property Insights of 8-{[5-(4-Isopropylphenyl)thieno[2,3-d]pyrimidin-4-yl]oxy}-2-methylquinoline
The XLogP value of 7.13062 indicates that 8-{[5-(4-Isopropylphenyl)thieno[2,3-d]pyrimidin-4-yl]oxy}-2-methylquinoline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 47.9 Ų, 8-{[5-(4-Isopropylphenyl)thieno[2,3-d]pyrimidin-4-yl]oxy}-2-methylquinoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 8-{[5-(4-Isopropylphenyl)thieno[2,3-d]pyrimidin-4-yl]oxy}-2-methylquinoline has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 8-{[5-(4-Isopropylphenyl)thieno[2,3-d]pyrimidin-4-yl]oxy}-2-methylquinoline?
The CAS number of 8-{[5-(4-Isopropylphenyl)thieno[2,3-d]pyrimidin-4-yl]oxy}-2-methylquinoline is 379244-67-4.
What is the molecular formula of 8-{[5-(4-Isopropylphenyl)thieno[2,3-d]pyrimidin-4-yl]oxy}-2-methylquinoline?
The molecular formula of 8-{[5-(4-Isopropylphenyl)thieno[2,3-d]pyrimidin-4-yl]oxy}-2-methylquinoline is C25H21N3OS.
What is the molecular weight of 8-{[5-(4-Isopropylphenyl)thieno[2,3-d]pyrimidin-4-yl]oxy}-2-methylquinoline?
The molecular weight of 8-{[5-(4-Isopropylphenyl)thieno[2,3-d]pyrimidin-4-yl]oxy}-2-methylquinoline is 411.14 g/mol.
Where can I buy 8-{[5-(4-Isopropylphenyl)thieno[2,3-d]pyrimidin-4-yl]oxy}-2-methylquinoline?
You can request a quote for 8-{[5-(4-Isopropylphenyl)thieno[2,3-d]pyrimidin-4-yl]oxy}-2-methylquinoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 8-{[5-(4-Isopropylphenyl)thieno[2,3-d]pyrimidin-4-yl]oxy}-2-methylquinoline?
Yes, KEHONG BIO provides custom synthesis services for 8-{[5-(4-Isopropylphenyl)thieno[2,3-d]pyrimidin-4-yl]oxy}-2-methylquinoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.