AF-399/40684317
TL;DR: AF-399/40684317 (CAS 379244-49-2) is a chemical compound with molecular formula C19H14ClFN4OS and molecular weight 400.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-(3-chloro-4-fluorophenyl)-2-[(5-methyl-[1,2,4]triazolo[4,3-a]quinolin-1-yl)sulfanyl]acetamide
Also Known As: AF-399/40684317, F1143-4637, N-(3-CHLORO-4-FLUOROPHENYL)-2-({5-METHYL-[1,2,4]TRIAZOLO[4,3-A]QUINOLIN-1-YL}SULFANYL)ACETAMIDE, N-(3-chloro-4-fluorophenyl)-2-[(5-methyl-[1,2,4]triazolo[4,3-a]quinolin-1-yl)sulfanyl]acetamide, N-(3-chloro-4-fluorophenyl)-2-((5-methyl-[1,2,4]triazolo[4,3-a]quinolin-1-yl)thio)acetamide
| Molecular Formula | C19H14ClFN4OS |
|---|---|
| Molecular Weight | 400.06 g/mol |
| LogP | 4.71422 |
| Topological Polar Surface Area | 59.29 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 400.0561 |
| Heavy Atoms | 27 |
| Complexity | 1177.2667 |
Chemical Identifiers
| CAS Number | 379244-49-2 |
|---|---|
| SMILES | CC1=CC2=NN=C(N2C3=CC=CC=C13)SCC(=O)NC4=CC(=C(C=C4)F)Cl |
Product Overview
AF-399/40684317 (CAS 379244-49-2), with molecular formula C19H14ClFN4OS and molecular weight 400.06 g/mol. IUPAC: N-(3-chloro-4-fluorophenyl)-2-[(5-methyl-[1,2,4]triazolo[4,3-a]quinolin-1-yl)sulfanyl]acetamide.
Chemical Property Profile of AF-399/40684317
Property Insights of AF-399/40684317
The XLogP value of 4.71422 indicates that AF-399/40684317 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 59.29 Ų, AF-399/40684317 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, AF-399/40684317 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AF-399/40684317?
The CAS number of AF-399/40684317 is 379244-49-2.
What is the molecular formula of AF-399/40684317?
The molecular formula of AF-399/40684317 is C19H14ClFN4OS.
What is the molecular weight of AF-399/40684317?
The molecular weight of AF-399/40684317 is 400.06 g/mol.
Where can I buy AF-399/40684317?
You can request a quote for AF-399/40684317 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AF-399/40684317?
Yes, KEHONG BIO provides custom synthesis services for AF-399/40684317 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.