AF-399/40920990
TL;DR: AF-399/40920990 (CAS 379239-61-9) is a chemical compound with molecular formula C20H15F3N4OS and molecular weight 416.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[(5-methyl-[1,2,4]triazolo[4,3-a]quinolin-1-yl)sulfanyl]-N-[2-(trifluoromethyl)phenyl]acetamide
Also Known As: AF-399/40920990, F1142-1068, 2-((5-methyl-[1,2,4]triazolo[4,3-a]quinolin-1-yl)thio)-N-(2-(trifluoromethyl)phenyl)acetamide, 2-({5-METHYL-[1,2,4]TRIAZOLO[4,3-A]QUINOLIN-1-YL}SULFANYL)-N-[2-(TRIFLUOROMETHYL)PHENYL]ACETAMIDE, 2-[(5-methyl-[1,2,4]triazolo[4,3-a]quinolin-1-yl)sulfanyl]-N-[2-(trifluoromethyl)phenyl]acetamide
| Molecular Formula | C20H15F3N4OS |
|---|---|
| Molecular Weight | 416.09 g/mol |
| LogP | 4.94052 |
| Topological Polar Surface Area | 59.29 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 416.09186 |
| Heavy Atoms | 29 |
| Complexity | 1219.5233 |
Chemical Identifiers
| CAS Number | 379239-61-9 |
|---|---|
| SMILES | CC1=CC2=NN=C(N2C3=CC=CC=C13)SCC(=O)NC4=CC=CC=C4C(F)(F)F |
Product Overview
AF-399/40920990 (CAS 379239-61-9), with molecular formula C20H15F3N4OS and molecular weight 416.09 g/mol. IUPAC: 2-[(5-methyl-[1,2,4]triazolo[4,3-a]quinolin-1-yl)sulfanyl]-N-[2-(trifluoromethyl)phenyl]acetamide.
Chemical Property Profile of AF-399/40920990
Property Insights of AF-399/40920990
The XLogP value of 4.94052 indicates that AF-399/40920990 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 59.29 Ų, AF-399/40920990 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, AF-399/40920990 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AF-399/40920990?
The CAS number of AF-399/40920990 is 379239-61-9.
What is the molecular formula of AF-399/40920990?
The molecular formula of AF-399/40920990 is C20H15F3N4OS.
What is the molecular weight of AF-399/40920990?
The molecular weight of AF-399/40920990 is 416.09 g/mol.
Where can I buy AF-399/40920990?
You can request a quote for AF-399/40920990 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AF-399/40920990?
Yes, KEHONG BIO provides custom synthesis services for AF-399/40920990 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.