F1143-1046 structure

F1143-1046

TL;DR: F1143-1046 (CAS 379239-19-7) is a chemical compound with molecular formula C21H16FN3O2S3 and molecular weight 457.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-(4-fluorophenyl)-2-(4-oxo-3-prop-2-enyl-5-thiophen-2-ylthieno[2,3-d]pyrimidin-2-yl)sulfanylacetamide

Also Known As: F1143-1046, N-(4-fluorophenyl)-2-{[4-oxo-3-(prop-2-en-1-yl)-5-(thiophen-2-yl)-3H,4H-thieno[2,3-d]pyrimidin-2-yl]sulfanyl}acetamide, N-(4-fluorophenyl)-2-(4-oxo-3-prop-2-enyl-5-thiophen-2-ylthieno[2,3-d]pyrimidin-2-yl)sulfanylacetamide, 2-((3-allyl-4-oxo-5-(thiophen-2-yl)-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)-N-(4-fluorophenyl)acetamide, N-(4-fluorophenyl)-2-{[4-oxo-3-(prop-2-en-1-yl)-5-(thiophen-2-yl)-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl]sulfanyl}acetamide

CAS: 379239-19-7
Molecular Formula C21H16FN3O2S3
Molecular Weight 457.04 g/mol
LogP 5.2424
Topological Polar Surface Area 63.99 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 6
Rotatable Bonds 7
Exact Mass 457.03888
Heavy Atoms 30
Complexity 1261.3865

Chemical Identifiers

CAS Number 379239-19-7
SMILES C=CCN1C(=O)C2=C(N=C1SCC(=O)NC3=CC=C(C=C3)F)SC=C2C4=CC=CS4

Product Overview

F1143-1046 (CAS 379239-19-7), with molecular formula C21H16FN3O2S3 and molecular weight 457.04 g/mol. IUPAC: N-(4-fluorophenyl)-2-(4-oxo-3-prop-2-enyl-5-thiophen-2-ylthieno[2,3-d]pyrimidin-2-yl)sulfanylacetamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of F1143-1046

XLogP
5.2424
TPSA (Topological Polar Surface Area)
63.99
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
6
Rotatable Bonds
7
Heavy Atoms
30
Complexity
1261.3865
Exact Mass
457.03888
Monoisotopic Mass
457.03888
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of F1143-1046

The XLogP value of 5.2424 indicates that F1143-1046 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 63.99 Ų falls within the moderate polarity range, balancing permeability and solubility for F1143-1046. Following Lipinski's Rule of Five, F1143-1046 has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of F1143-1046?

The CAS number of F1143-1046 is 379239-19-7.

What is the molecular formula of F1143-1046?

The molecular formula of F1143-1046 is C21H16FN3O2S3.

What is the molecular weight of F1143-1046?

The molecular weight of F1143-1046 is 457.04 g/mol.

Where can I buy F1143-1046?

You can request a quote for F1143-1046 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for F1143-1046?

Yes, KEHONG BIO provides custom synthesis services for F1143-1046 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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