![1-{[4-(Pyrimidin-2-yl)piperazin-1-yl]methyl}naphthalen-2-ol structure](/static/products/3792/379237-74-8.webp)
1-{[4-(Pyrimidin-2-yl)piperazin-1-yl]methyl}naphthalen-2-ol
TL;DR: 1-{[4-(Pyrimidin-2-yl)piperazin-1-yl]methyl}naphthalen-2-ol (CAS 379237-74-8) is a chemical compound with molecular formula C19H20N4O and molecular weight 320.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(4-pyrimidin-2-ylpiperazin-1-yl)methyl]naphthalen-2-ol
Also Known As: AF-399/40827553, 1-[(4-pyrimidin-2-ylpiperazin-1-yl)methyl]naphthalen-2-ol, 1-{[4-(pyrimidin-2-yl)piperazin-1-yl]methyl}naphthalen-2-ol, 1-[(4-pyrimidin-2-ylpiperazinyl)methyl]naphthalen-2-ol, 1-{[4-(2-pyrimidinyl)-1-piperazinyl]methyl}-2-naphthol
| Molecular Formula | C19H20N4O |
|---|---|
| Molecular Weight | 320.16 g/mol |
| LogP | 2.9 |
| Topological Polar Surface Area | 52.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 320.1637 |
| Heavy Atoms | 24 |
| Complexity | 393.0 |
Chemical Identifiers
| CAS Number | 379237-74-8 |
|---|---|
| SMILES | C1CN(CCN1CC2=C(C=CC3=CC=CC=C32)O)C4=NC=CC=N4 |
| InChIKey | PCBQNKXXRDXNPA-UHFFFAOYSA-N |
Product Overview
1-{[4-(Pyrimidin-2-yl)piperazin-1-yl]methyl}naphthalen-2-ol (CAS 379237-74-8), with molecular formula C19H20N4O and molecular weight 320.16 g/mol. IUPAC: 1-[(4-pyrimidin-2-ylpiperazin-1-yl)methyl]naphthalen-2-ol.
Chemical Property Profile of 1-{[4-(Pyrimidin-2-yl)piperazin-1-yl]methyl}naphthalen-2-ol
Property Insights of 1-{[4-(Pyrimidin-2-yl)piperazin-1-yl]methyl}naphthalen-2-ol
The XLogP value of 2.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-{[4-(Pyrimidin-2-yl)piperazin-1-yl]methyl}naphthalen-2-ol. With a topological polar surface area (TPSA) of 52.5 Ų, 1-{[4-(Pyrimidin-2-yl)piperazin-1-yl]methyl}naphthalen-2-ol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-{[4-(Pyrimidin-2-yl)piperazin-1-yl]methyl}naphthalen-2-ol has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-{[4-(Pyrimidin-2-yl)piperazin-1-yl]methyl}naphthalen-2-ol?
The CAS number of 1-{[4-(Pyrimidin-2-yl)piperazin-1-yl]methyl}naphthalen-2-ol is 379237-74-8.
What is the molecular formula of 1-{[4-(Pyrimidin-2-yl)piperazin-1-yl]methyl}naphthalen-2-ol?
The molecular formula of 1-{[4-(Pyrimidin-2-yl)piperazin-1-yl]methyl}naphthalen-2-ol is C19H20N4O.
What is the molecular weight of 1-{[4-(Pyrimidin-2-yl)piperazin-1-yl]methyl}naphthalen-2-ol?
The molecular weight of 1-{[4-(Pyrimidin-2-yl)piperazin-1-yl]methyl}naphthalen-2-ol is 320.16 g/mol.
Where can I buy 1-{[4-(Pyrimidin-2-yl)piperazin-1-yl]methyl}naphthalen-2-ol?
You can request a quote for 1-{[4-(Pyrimidin-2-yl)piperazin-1-yl]methyl}naphthalen-2-ol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-{[4-(Pyrimidin-2-yl)piperazin-1-yl]methyl}naphthalen-2-ol?
Yes, KEHONG BIO provides custom synthesis services for 1-{[4-(Pyrimidin-2-yl)piperazin-1-yl]methyl}naphthalen-2-ol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.