(E)-methyl 2-(3-(3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)acrylamido)-4-methylthiazole-5-carboxylate
TL;DR: (E)-methyl 2-(3-(3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)acrylamido)-4-methylthiazole-5-carboxylate (CAS 378770-37-7) is a chemical compound with molecular formula C24H19FN4O3S and molecular weight 462.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
methyl 2-[[(E)-3-[3-(4-fluorophenyl)-1-phenylpyrazol-4-yl]prop-2-enoyl]amino]-4-methyl-1,3-thiazole-5-carboxylate
Also Known As: (E)-methyl 2-(3-(3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)acrylamido)-4-methylthiazole-5-carboxylate, methyl 2-({(2E)-3-[3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl]prop-2-enoyl}amino)-4-methyl-1,3-thiazole-5-carboxylate, methyl 2-[[(E)-3-[3-(4-fluorophenyl)-1-phenylpyrazol-4-yl]prop-2-enoyl]amino]-4-methyl-1,3-thiazole-5-carboxylate
| Molecular Formula | C24H19FN4O3S |
|---|---|
| Molecular Weight | 462.12 g/mol |
| LogP | 4.88182 |
| Topological Polar Surface Area | 86.11 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 462.11618 |
| Heavy Atoms | 33 |
| Complexity | 1327.7606 |
Chemical Identifiers
| CAS Number | 378770-37-7 |
|---|---|
| SMILES | CC1=C(SC(=N1)NC(=O)/C=C/C2=CN(N=C2C3=CC=C(C=C3)F)C4=CC=CC=C4)C(=O)OC |
Product Overview
(E)-methyl 2-(3-(3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)acrylamido)-4-methylthiazole-5-carboxylate (CAS 378770-37-7), with molecular formula C24H19FN4O3S and molecular weight 462.12 g/mol. IUPAC: methyl 2-[[(E)-3-[3-(4-fluorophenyl)-1-phenylpyrazol-4-yl]prop-2-enoyl]amino]-4-methyl-1,3-thiazole-5-carboxylate.
Chemical Property Profile of (E)-methyl 2-(3-(3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)acrylamido)-4-methylthiazole-5-carboxylate
Property Insights of (E)-methyl 2-(3-(3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)acrylamido)-4-methylthiazole-5-carboxylate
The XLogP value of 4.88182 indicates that (E)-methyl 2-(3-(3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)acrylamido)-4-methylthiazole-5-carboxylate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 86.11 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-methyl 2-(3-(3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)acrylamido)-4-methylthiazole-5-carboxylate. Following Lipinski's Rule of Five, (E)-methyl 2-(3-(3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)acrylamido)-4-methylthiazole-5-carboxylate has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-methyl 2-(3-(3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)acrylamido)-4-methylthiazole-5-carboxylate?
The CAS number of (E)-methyl 2-(3-(3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)acrylamido)-4-methylthiazole-5-carboxylate is 378770-37-7.
What is the molecular formula of (E)-methyl 2-(3-(3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)acrylamido)-4-methylthiazole-5-carboxylate?
The molecular formula of (E)-methyl 2-(3-(3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)acrylamido)-4-methylthiazole-5-carboxylate is C24H19FN4O3S.
What is the molecular weight of (E)-methyl 2-(3-(3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)acrylamido)-4-methylthiazole-5-carboxylate?
The molecular weight of (E)-methyl 2-(3-(3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)acrylamido)-4-methylthiazole-5-carboxylate is 462.12 g/mol.
Where can I buy (E)-methyl 2-(3-(3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)acrylamido)-4-methylthiazole-5-carboxylate?
You can request a quote for (E)-methyl 2-(3-(3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)acrylamido)-4-methylthiazole-5-carboxylate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-methyl 2-(3-(3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)acrylamido)-4-methylthiazole-5-carboxylate?
Yes, KEHONG BIO provides custom synthesis services for (E)-methyl 2-(3-(3-(4-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)acrylamido)-4-methylthiazole-5-carboxylate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.