1-(1,1,1,3,3,3-Hexafluoro-2-methylpropan-2-yl)-3-(2-hydroxyphenyl)urea
TL;DR: 1-(1,1,1,3,3,3-Hexafluoro-2-methylpropan-2-yl)-3-(2-hydroxyphenyl)urea (CAS 378765-06-1) is a chemical compound with molecular formula C11H10F6N2O2 and molecular weight 316.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-(1,1,1,3,3,3-hexafluoro-2-methylpropan-2-yl)-3-(2-hydroxyphenyl)urea
Also Known As: 1-(1,1,1,3,3,3-hexafluoro-2-methylpropan-2-yl)-3-(2-hydroxyphenyl)urea, N-(2-hydroxyphenyl)-N'-[2,2,2-trifluoro-1-methyl-1-(trifluoromethyl)ethyl]urea
| Molecular Formula | C11H10F6N2O2 |
|---|---|
| Molecular Weight | 316.06 g/mol |
| LogP | 3.397 |
| Topological Polar Surface Area | 61.36 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 316.06464 |
| Heavy Atoms | 21 |
| Complexity | 512.1801 |
Chemical Identifiers
| CAS Number | 378765-06-1 |
|---|---|
| SMILES | CC(C(F)(F)F)(C(F)(F)F)NC(=O)NC1=CC=CC=C1O |
Product Overview
1-(1,1,1,3,3,3-Hexafluoro-2-methylpropan-2-yl)-3-(2-hydroxyphenyl)urea (CAS 378765-06-1), with molecular formula C11H10F6N2O2 and molecular weight 316.06 g/mol. IUPAC: 1-(1,1,1,3,3,3-hexafluoro-2-methylpropan-2-yl)-3-(2-hydroxyphenyl)urea.
Chemical Property Profile of 1-(1,1,1,3,3,3-Hexafluoro-2-methylpropan-2-yl)-3-(2-hydroxyphenyl)urea
Property Insights of 1-(1,1,1,3,3,3-Hexafluoro-2-methylpropan-2-yl)-3-(2-hydroxyphenyl)urea
The XLogP value of 3.397 indicates that 1-(1,1,1,3,3,3-Hexafluoro-2-methylpropan-2-yl)-3-(2-hydroxyphenyl)urea is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 61.36 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-(1,1,1,3,3,3-Hexafluoro-2-methylpropan-2-yl)-3-(2-hydroxyphenyl)urea. Following Lipinski's Rule of Five, 1-(1,1,1,3,3,3-Hexafluoro-2-methylpropan-2-yl)-3-(2-hydroxyphenyl)urea has 3 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(1,1,1,3,3,3-Hexafluoro-2-methylpropan-2-yl)-3-(2-hydroxyphenyl)urea?
The CAS number of 1-(1,1,1,3,3,3-Hexafluoro-2-methylpropan-2-yl)-3-(2-hydroxyphenyl)urea is 378765-06-1.
What is the molecular formula of 1-(1,1,1,3,3,3-Hexafluoro-2-methylpropan-2-yl)-3-(2-hydroxyphenyl)urea?
The molecular formula of 1-(1,1,1,3,3,3-Hexafluoro-2-methylpropan-2-yl)-3-(2-hydroxyphenyl)urea is C11H10F6N2O2.
What is the molecular weight of 1-(1,1,1,3,3,3-Hexafluoro-2-methylpropan-2-yl)-3-(2-hydroxyphenyl)urea?
The molecular weight of 1-(1,1,1,3,3,3-Hexafluoro-2-methylpropan-2-yl)-3-(2-hydroxyphenyl)urea is 316.06 g/mol.
Where can I buy 1-(1,1,1,3,3,3-Hexafluoro-2-methylpropan-2-yl)-3-(2-hydroxyphenyl)urea?
You can request a quote for 1-(1,1,1,3,3,3-Hexafluoro-2-methylpropan-2-yl)-3-(2-hydroxyphenyl)urea directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(1,1,1,3,3,3-Hexafluoro-2-methylpropan-2-yl)-3-(2-hydroxyphenyl)urea?
Yes, KEHONG BIO provides custom synthesis services for 1-(1,1,1,3,3,3-Hexafluoro-2-methylpropan-2-yl)-3-(2-hydroxyphenyl)urea and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.