F1103-0272
TL;DR: F1103-0272 (CAS 378757-30-3) is a chemical compound with molecular formula C18H21ClN4O2S2 and molecular weight 424.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-[(5E)-5-[(2-chlorophenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-N-(4-methylpiperazin-1-yl)propanamide
Also Known As: F1103-0272, 3-[(5E)-5-[(2-chlorophenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-N-(4-methylpiperazin-1-yl)propanamide, (E)-3-(5-(2-chlorobenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)-N-(4-methylpiperazin-1-yl)propanamide, (E)-5-[(o-chlorophenyl)methylene]-3-[3-(4-methyl-1-piperazinylamino)-3-oxopropyl]-2-thioxo-1,3-thiazolidin-4-one, 3-{5-[(2-chlorophenyl)methylene]-4-oxo-2-thioxo(1,3-thiazolidin-3-yl)}-N-(4-me thylpiperazinyl)propanamide
| Molecular Formula | C18H21ClN4O2S2 |
|---|---|
| Molecular Weight | 424.08 g/mol |
| LogP | 2.2099 |
| Topological Polar Surface Area | 55.89 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 424.07944 |
| Heavy Atoms | 27 |
| Complexity | 778.38007 |
Chemical Identifiers
| CAS Number | 378757-30-3 |
|---|---|
| SMILES | CN1CCN(CC1)NC(=O)CCN2C(=O)/C(=C\C3=CC=CC=C3Cl)/SC2=S |
Product Overview
F1103-0272 (CAS 378757-30-3), with molecular formula C18H21ClN4O2S2 and molecular weight 424.08 g/mol. IUPAC: 3-[(5E)-5-[(2-chlorophenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-N-(4-methylpiperazin-1-yl)propanamide.
Chemical Property Profile of F1103-0272
Property Insights of F1103-0272
The XLogP value of 2.2099 suggests moderate lipophilicity, balancing water solubility and membrane permeability for F1103-0272. With a topological polar surface area (TPSA) of 55.89 Ų, F1103-0272 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, F1103-0272 has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of F1103-0272?
The CAS number of F1103-0272 is 378757-30-3.
What is the molecular formula of F1103-0272?
The molecular formula of F1103-0272 is C18H21ClN4O2S2.
What is the molecular weight of F1103-0272?
The molecular weight of F1103-0272 is 424.08 g/mol.
Where can I buy F1103-0272?
You can request a quote for F1103-0272 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for F1103-0272?
Yes, KEHONG BIO provides custom synthesis services for F1103-0272 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.