![2-[5-(1,1,2,2-tetrafluoroethyl)-1H-pyrazol-3-yl]phenol structure](/static/products/3787/378754-97-3.webp)
2-[5-(1,1,2,2-tetrafluoroethyl)-1H-pyrazol-3-yl]phenol
TL;DR: 2-[5-(1,1,2,2-tetrafluoroethyl)-1H-pyrazol-3-yl]phenol (CAS 378754-97-3) is a chemical compound with molecular formula C11H8F4N2O and molecular weight 260.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[5-(1,1,2,2-tetrafluoroethyl)-1H-pyrazol-3-yl]phenol
Also Known As: 2-[5-(1,1,2,2-tetrafluoroethyl)-1H-pyrazol-3-yl]phenol, 5-(2-HYDROXYPHENYL)-3-(1,1,2,2-TETRAFLUOROETHYL)PYRAZOLE, 2-[5-[1,1,2,2-Tetrakis(Fluoranyl)ethyl]-1~{h}-Pyrazol-3-Yl]phenol, 2-[5-(1,1,2,2-tetrafluoroethyl)pyrazol-3-yl]phenol, 2-(3-(1,1,2,2-Tetrafluoroethyl)-1H-pyrazol-5-yl)phenol
| Molecular Formula | C11H8F4N2O |
|---|---|
| Molecular Weight | 260.06 g/mol |
| LogP | 2.9 |
| Topological Polar Surface Area | 48.9 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 260.05728 |
| Heavy Atoms | 18 |
| Complexity | 290.0 |
Chemical Identifiers
| CAS Number | 378754-97-3 |
|---|---|
| SMILES | C1=CC=C(C(=C1)C2=NNC(=C2)C(C(F)F)(F)F)O |
| InChIKey | AZBWBPKELVSJMM-UHFFFAOYSA-N |
Product Overview
2-[5-(1,1,2,2-tetrafluoroethyl)-1H-pyrazol-3-yl]phenol (CAS 378754-97-3), with molecular formula C11H8F4N2O and molecular weight 260.06 g/mol. IUPAC: 2-[5-(1,1,2,2-tetrafluoroethyl)-1H-pyrazol-3-yl]phenol.
Chemical Property Profile of 2-[5-(1,1,2,2-tetrafluoroethyl)-1H-pyrazol-3-yl]phenol
Property Insights of 2-[5-(1,1,2,2-tetrafluoroethyl)-1H-pyrazol-3-yl]phenol
The XLogP value of 2.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-[5-(1,1,2,2-tetrafluoroethyl)-1H-pyrazol-3-yl]phenol. With a topological polar surface area (TPSA) of 48.9 Ų, 2-[5-(1,1,2,2-tetrafluoroethyl)-1H-pyrazol-3-yl]phenol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-[5-(1,1,2,2-tetrafluoroethyl)-1H-pyrazol-3-yl]phenol has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-[5-(1,1,2,2-tetrafluoroethyl)-1H-pyrazol-3-yl]phenol?
The CAS number of 2-[5-(1,1,2,2-tetrafluoroethyl)-1H-pyrazol-3-yl]phenol is 378754-97-3.
What is the molecular formula of 2-[5-(1,1,2,2-tetrafluoroethyl)-1H-pyrazol-3-yl]phenol?
The molecular formula of 2-[5-(1,1,2,2-tetrafluoroethyl)-1H-pyrazol-3-yl]phenol is C11H8F4N2O.
What is the molecular weight of 2-[5-(1,1,2,2-tetrafluoroethyl)-1H-pyrazol-3-yl]phenol?
The molecular weight of 2-[5-(1,1,2,2-tetrafluoroethyl)-1H-pyrazol-3-yl]phenol is 260.06 g/mol.
Where can I buy 2-[5-(1,1,2,2-tetrafluoroethyl)-1H-pyrazol-3-yl]phenol?
You can request a quote for 2-[5-(1,1,2,2-tetrafluoroethyl)-1H-pyrazol-3-yl]phenol directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-[5-(1,1,2,2-tetrafluoroethyl)-1H-pyrazol-3-yl]phenol?
Yes, KEHONG BIO provides custom synthesis services for 2-[5-(1,1,2,2-tetrafluoroethyl)-1H-pyrazol-3-yl]phenol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.