Pfkfb3-IN-1 structure

Pfkfb3-IN-1

TL;DR: Pfkfb3-IN-1 (CAS 378236-96-5) is a chemical compound with molecular formula C17H14N4O2 and molecular weight 306.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-[4-[(2-amino-3-cyano-1H-indol-5-yl)oxy]phenyl]acetamide

Also Known As: PFKFB3-IN-1, 5-(4-acetylaminophenoxy)-2-amino-1H-indole-3-carbonitrile, n-(4-((2-amino-3-cyano-1h-indol-5-yl)oxy)phenyl)acetamide, N-[4-[(2-amino-3-cyano-1H-indol-5-yl)oxy]phenyl]acetamide

CAS: 378236-96-5
Molecular Formula C17H14N4O2
Molecular Weight 306.11 g/mol
LogP 3.37248
Topological Polar Surface Area 103.93 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 4
Rotatable Bonds 3
Exact Mass 306.11166
Heavy Atoms 23
Complexity 920.1566

Chemical Identifiers

CAS Number 378236-96-5
SMILES CC(=O)NC1=CC=C(C=C1)OC2=CC3=C(C=C2)NC(=C3C#N)N

Product Overview

Pfkfb3-IN-1 (CAS 378236-96-5), with molecular formula C17H14N4O2 and molecular weight 306.11 g/mol. IUPAC: N-[4-[(2-amino-3-cyano-1H-indol-5-yl)oxy]phenyl]acetamide.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Pfkfb3-IN-1

XLogP
3.37248
TPSA (Topological Polar Surface Area)
103.93
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
4
Rotatable Bonds
3
Heavy Atoms
23
Complexity
920.1566
Exact Mass
306.11166
Monoisotopic Mass
306.11166
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Pfkfb3-IN-1

The XLogP value of 3.37248 indicates that Pfkfb3-IN-1 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 103.93 Ų falls within the moderate polarity range, balancing permeability and solubility for Pfkfb3-IN-1. Following Lipinski's Rule of Five, Pfkfb3-IN-1 has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Pfkfb3-IN-1?

The CAS number of Pfkfb3-IN-1 is 378236-96-5.

What is the molecular formula of Pfkfb3-IN-1?

The molecular formula of Pfkfb3-IN-1 is C17H14N4O2.

What is the molecular weight of Pfkfb3-IN-1?

The molecular weight of Pfkfb3-IN-1 is 306.11 g/mol.

Where can I buy Pfkfb3-IN-1?

You can request a quote for Pfkfb3-IN-1 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Pfkfb3-IN-1?

Yes, KEHONG BIO provides custom synthesis services for Pfkfb3-IN-1 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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