4-methylidene-3-(4-methylphenyl)-1H-quinazolin-2-one
TL;DR: 4-methylidene-3-(4-methylphenyl)-1H-quinazolin-2-one (CAS 378207-92-2) is a chemical compound with molecular formula C16H14N2O and molecular weight 250.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-methylidene-3-(4-methylphenyl)-1H-quinazolin-2-one
Also Known As: ChemDiv3_002576, 4-methylidene-3-(4-methylphenyl)-1H-quinazolin-2-one, 4-methylene-3-(p-tolyl)-3,4-dihydroquinazolin-2(1H)-one, 4-methylene-3-(4-methylphenyl)-3,4-dihydro-2(1H)-quinazolinone, 4-methylidene-3-(4-methylphenyl)-3,4-dihydroquinazolin-2(1H)-one
| Molecular Formula | C16H14N2O |
|---|---|
| Molecular Weight | 250.11 g/mol |
| LogP | 3.2 |
| Topological Polar Surface Area | 32.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 1 |
| Exact Mass | 250.11061 |
| Heavy Atoms | 19 |
| Complexity | 371.0 |
Chemical Identifiers
| CAS Number | 378207-92-2 |
|---|---|
| SMILES | CC1=CC=C(C=C1)N2C(=C)C3=CC=CC=C3NC2=O |
| InChIKey | ZCRRXPCYLDLVPW-UHFFFAOYSA-N |
Product Overview
4-methylidene-3-(4-methylphenyl)-1H-quinazolin-2-one (CAS 378207-92-2), with molecular formula C16H14N2O and molecular weight 250.11 g/mol. IUPAC: 4-methylidene-3-(4-methylphenyl)-1H-quinazolin-2-one.
Chemical Property Profile of 4-methylidene-3-(4-methylphenyl)-1H-quinazolin-2-one
Property Insights of 4-methylidene-3-(4-methylphenyl)-1H-quinazolin-2-one
The XLogP value of 3.2 indicates that 4-methylidene-3-(4-methylphenyl)-1H-quinazolin-2-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 32.3 Ų, 4-methylidene-3-(4-methylphenyl)-1H-quinazolin-2-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-methylidene-3-(4-methylphenyl)-1H-quinazolin-2-one has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-methylidene-3-(4-methylphenyl)-1H-quinazolin-2-one?
The CAS number of 4-methylidene-3-(4-methylphenyl)-1H-quinazolin-2-one is 378207-92-2.
What is the molecular formula of 4-methylidene-3-(4-methylphenyl)-1H-quinazolin-2-one?
The molecular formula of 4-methylidene-3-(4-methylphenyl)-1H-quinazolin-2-one is C16H14N2O.
What is the molecular weight of 4-methylidene-3-(4-methylphenyl)-1H-quinazolin-2-one?
The molecular weight of 4-methylidene-3-(4-methylphenyl)-1H-quinazolin-2-one is 250.11 g/mol.
Where can I buy 4-methylidene-3-(4-methylphenyl)-1H-quinazolin-2-one?
You can request a quote for 4-methylidene-3-(4-methylphenyl)-1H-quinazolin-2-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-methylidene-3-(4-methylphenyl)-1H-quinazolin-2-one?
Yes, KEHONG BIO provides custom synthesis services for 4-methylidene-3-(4-methylphenyl)-1H-quinazolin-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.