(E)-7-(but-2-en-1-yl)-8-((2-chloro-6-fluorobenzyl)thio)-3-methyl-1H-purine-2,6(3H,7H)-dione structure

(E)-7-(but-2-en-1-yl)-8-((2-chloro-6-fluorobenzyl)thio)-3-methyl-1H-purine-2,6(3H,7H)-dione

TL;DR: (E)-7-(but-2-en-1-yl)-8-((2-chloro-6-fluorobenzyl)thio)-3-methyl-1H-purine-2,6(3H,7H)-dione (CAS 378206-63-4) is a chemical compound with molecular formula C17H16ClFN4O2S and molecular weight 394.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

7-[(E)-but-2-enyl]-8-[(2-chloro-6-fluorophenyl)methylsulfanyl]-3-methylpurine-2,6-dione

Also Known As: (E)-7-(but-2-en-1-yl)-8-((2-chloro-6-fluorobenzyl)thio)-3-methyl-1H-purine-2,6(3H,7H)-dione, 7-[(2E)-but-2-en-1-yl]-8-{[(2-chloro-6-fluorophenyl)methyl]sulfanyl}-3-methyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione, 7-[(E)-but-2-enyl]-8-[(2-chloro-6-fluorophenyl)methylsulfanyl]-3-methylpurine-2,6-dione, 7-((2E)but-2-enyl)-8-[(2-chloro-6-fluorophenyl)methylthio]-3-methyl-1,3,7-trih ydropurine-2,6-dione, 7-(2-BUTENYL)-8-((2-CL-6-FLUOROBENZYL)THIO)-3-ME-3,7-DIHYDRO-1H-PURINE-2,6-DIONE

CAS: 378206-63-4
Molecular Formula C17H16ClFN4O2S
Molecular Weight 394.07 g/mol
LogP 3.0842
Topological Polar Surface Area 72.68 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 4
Rotatable Bonds 5
Exact Mass 394.06665
Heavy Atoms 26
Complexity 1096.124

Chemical Identifiers

CAS Number 378206-63-4
SMILES C/C=C/CN1C2=C(N=C1SCC3=C(C=CC=C3Cl)F)N(C(=O)NC2=O)C

Product Overview

(E)-7-(but-2-en-1-yl)-8-((2-chloro-6-fluorobenzyl)thio)-3-methyl-1H-purine-2,6(3H,7H)-dione (CAS 378206-63-4), with molecular formula C17H16ClFN4O2S and molecular weight 394.07 g/mol. IUPAC: 7-[(E)-but-2-enyl]-8-[(2-chloro-6-fluorophenyl)methylsulfanyl]-3-methylpurine-2,6-dione.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of (E)-7-(but-2-en-1-yl)-8-((2-chloro-6-fluorobenzyl)thio)-3-methyl-1H-purine-2,6(3H,7H)-dione

XLogP
3.0842
TPSA (Topological Polar Surface Area)
72.68
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
4
Rotatable Bonds
5
Heavy Atoms
26
Complexity
1096.124
Exact Mass
394.06665
Monoisotopic Mass
394.06665
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of (E)-7-(but-2-en-1-yl)-8-((2-chloro-6-fluorobenzyl)thio)-3-methyl-1H-purine-2,6(3H,7H)-dione

The XLogP value of 3.0842 indicates that (E)-7-(but-2-en-1-yl)-8-((2-chloro-6-fluorobenzyl)thio)-3-methyl-1H-purine-2,6(3H,7H)-dione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 72.68 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-7-(but-2-en-1-yl)-8-((2-chloro-6-fluorobenzyl)thio)-3-methyl-1H-purine-2,6(3H,7H)-dione. Following Lipinski's Rule of Five, (E)-7-(but-2-en-1-yl)-8-((2-chloro-6-fluorobenzyl)thio)-3-methyl-1H-purine-2,6(3H,7H)-dione has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of (E)-7-(but-2-en-1-yl)-8-((2-chloro-6-fluorobenzyl)thio)-3-methyl-1H-purine-2,6(3H,7H)-dione?

The CAS number of (E)-7-(but-2-en-1-yl)-8-((2-chloro-6-fluorobenzyl)thio)-3-methyl-1H-purine-2,6(3H,7H)-dione is 378206-63-4.

What is the molecular formula of (E)-7-(but-2-en-1-yl)-8-((2-chloro-6-fluorobenzyl)thio)-3-methyl-1H-purine-2,6(3H,7H)-dione?

The molecular formula of (E)-7-(but-2-en-1-yl)-8-((2-chloro-6-fluorobenzyl)thio)-3-methyl-1H-purine-2,6(3H,7H)-dione is C17H16ClFN4O2S.

What is the molecular weight of (E)-7-(but-2-en-1-yl)-8-((2-chloro-6-fluorobenzyl)thio)-3-methyl-1H-purine-2,6(3H,7H)-dione?

The molecular weight of (E)-7-(but-2-en-1-yl)-8-((2-chloro-6-fluorobenzyl)thio)-3-methyl-1H-purine-2,6(3H,7H)-dione is 394.07 g/mol.

Where can I buy (E)-7-(but-2-en-1-yl)-8-((2-chloro-6-fluorobenzyl)thio)-3-methyl-1H-purine-2,6(3H,7H)-dione?

You can request a quote for (E)-7-(but-2-en-1-yl)-8-((2-chloro-6-fluorobenzyl)thio)-3-methyl-1H-purine-2,6(3H,7H)-dione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for (E)-7-(but-2-en-1-yl)-8-((2-chloro-6-fluorobenzyl)thio)-3-methyl-1H-purine-2,6(3H,7H)-dione?

Yes, KEHONG BIO provides custom synthesis services for (E)-7-(but-2-en-1-yl)-8-((2-chloro-6-fluorobenzyl)thio)-3-methyl-1H-purine-2,6(3H,7H)-dione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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