AF-399/15599154
TL;DR: AF-399/15599154 (CAS 378196-90-8) is a chemical compound with molecular formula C21H23F2NO3 and molecular weight 375.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
ethyl 4-(2,6-difluorophenyl)-2,7,7-trimethyl-5-oxo-1,4,6,8-tetrahydroquinoline-3-carboxylate
Also Known As: AF-399/15599154, ethyl 4-(2,6-difluorophenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate, ethyl 4-(2,6-difluorophenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydro-3-quinolinecarboxylate, ethyl 4-(2,6-difluorophenyl)-2,7,7-trimethyl-5-oxo-1,4,6,7,8-pentahydroquinoli ne-3-carboxylate, ethyl 4-(2,6-difluorophenyl)-2,7,7-trimethyl-5-oxo-1,4,6,8-tetrahydroquinoline-3-carboxylate
| Molecular Formula | C21H23F2NO3 |
|---|---|
| Molecular Weight | 375.16 g/mol |
| LogP | 4.1319 |
| Topological Polar Surface Area | 55.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 375.1646 |
| Heavy Atoms | 27 |
| Complexity | 863.16296 |
Chemical Identifiers
| CAS Number | 378196-90-8 |
|---|---|
| SMILES | CCOC(=O)C1=C(NC2=C(C1C3=C(C=CC=C3F)F)C(=O)CC(C2)(C)C)C |
Product Overview
AF-399/15599154 (CAS 378196-90-8), with molecular formula C21H23F2NO3 and molecular weight 375.16 g/mol. IUPAC: ethyl 4-(2,6-difluorophenyl)-2,7,7-trimethyl-5-oxo-1,4,6,8-tetrahydroquinoline-3-carboxylate.
Chemical Property Profile of AF-399/15599154
Property Insights of AF-399/15599154
The XLogP value of 4.1319 indicates that AF-399/15599154 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 55.4 Ų, AF-399/15599154 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, AF-399/15599154 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AF-399/15599154?
The CAS number of AF-399/15599154 is 378196-90-8.
What is the molecular formula of AF-399/15599154?
The molecular formula of AF-399/15599154 is C21H23F2NO3.
What is the molecular weight of AF-399/15599154?
The molecular weight of AF-399/15599154 is 375.16 g/mol.
Where can I buy AF-399/15599154?
You can request a quote for AF-399/15599154 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AF-399/15599154?
Yes, KEHONG BIO provides custom synthesis services for AF-399/15599154 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.