Propyperone structure

Propyperone

TL;DR: Propyperone (CAS 3781-28-0) is a chemical compound with molecular formula C23H33FN2O2 and molecular weight 388.25 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

1-(4-fluorophenyl)-4-(4-piperidin-1-yl-4-propanoylpiperidin-1-yl)butan-1-one

Also Known As: Propyperone, Floropipeton, Propiperona, Propyperonum, Propyperone [INN]

CAS: 3781-28-0
Molecular Formula C23H33FN2O2
Molecular Weight 388.25 g/mol
LogP 3.3
Topological Polar Surface Area 40.6 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 5
Rotatable Bonds 8
Exact Mass 388.2526
Heavy Atoms 28
Complexity 517.0

Chemical Identifiers

CAS Number 3781-28-0
SMILES CCC(=O)C1(CCN(CC1)CCCC(=O)C2=CC=C(C=C2)F)N3CCCCC3
InChIKey JMIUUTJADPMZTQ-UHFFFAOYSA-N

Patent-Derived Application Labels

Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.

Pharmaceutical Intermediates (13 patents)

Product Overview

Propyperone (CAS 3781-28-0), with molecular formula C23H33FN2O2 and molecular weight 388.25 g/mol. IUPAC: 1-(4-fluorophenyl)-4-(4-piperidin-1-yl-4-propanoylpiperidin-1-yl)butan-1-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Propyperone

XLogP
3.3
TPSA (Topological Polar Surface Area)
40.6
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
5
Rotatable Bonds
8
Heavy Atoms
28
Complexity
517.0
Exact Mass
388.2526
Monoisotopic Mass
388.2526
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Propyperone

The XLogP value of 3.3 indicates that Propyperone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 40.6 Ų, Propyperone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Propyperone has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Propyperone?

The CAS number of Propyperone is 3781-28-0.

What is the molecular formula of Propyperone?

The molecular formula of Propyperone is C23H33FN2O2.

What is the molecular weight of Propyperone?

The molecular weight of Propyperone is 388.25 g/mol.

Where can I buy Propyperone?

You can request a quote for Propyperone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Propyperone?

Yes, KEHONG BIO provides custom synthesis services for Propyperone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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