2-chloro-4-(1-methyl-1H-imidazole-2-carbonyl)quinoline structure

2-chloro-4-(1-methyl-1H-imidazole-2-carbonyl)quinoline

TL;DR: 2-chloro-4-(1-methyl-1H-imidazole-2-carbonyl)quinoline (CAS 377769-46-5) is a chemical compound with molecular formula C14H10ClN3O and molecular weight 271.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(2-chloroquinolin-4-yl)-(1-methylimidazol-2-yl)methanone

Also Known As: 2-chloro-4-(1-methyl-1H-imidazole-2-carbonyl)quinoline, (2-chloroquinolin-4-yl)-(1-methylimidazol-2-yl)methanone

CAS: 377769-46-5
Molecular Formula C14H10ClN3O
Molecular Weight 271.05 g/mol
LogP 2.8527
Topological Polar Surface Area 47.78 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 3
Rotatable Bonds 2
Exact Mass 271.05124
Heavy Atoms 19
Complexity 779.21204

Chemical Identifiers

CAS Number 377769-46-5
SMILES CN1C=CN=C1C(=O)C2=CC(=NC3=CC=CC=C32)Cl

Product Overview

2-chloro-4-(1-methyl-1H-imidazole-2-carbonyl)quinoline (CAS 377769-46-5), with molecular formula C14H10ClN3O and molecular weight 271.05 g/mol. IUPAC: (2-chloroquinolin-4-yl)-(1-methylimidazol-2-yl)methanone.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 2-chloro-4-(1-methyl-1H-imidazole-2-carbonyl)quinoline

XLogP
2.8527
TPSA (Topological Polar Surface Area)
47.78
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
3
Rotatable Bonds
2
Heavy Atoms
19
Complexity
779.21204
Exact Mass
271.05124
Monoisotopic Mass
271.05124
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 2-chloro-4-(1-methyl-1H-imidazole-2-carbonyl)quinoline

The XLogP value of 2.8527 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-chloro-4-(1-methyl-1H-imidazole-2-carbonyl)quinoline. With a topological polar surface area (TPSA) of 47.78 Ų, 2-chloro-4-(1-methyl-1H-imidazole-2-carbonyl)quinoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-chloro-4-(1-methyl-1H-imidazole-2-carbonyl)quinoline has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 2-chloro-4-(1-methyl-1H-imidazole-2-carbonyl)quinoline?

The CAS number of 2-chloro-4-(1-methyl-1H-imidazole-2-carbonyl)quinoline is 377769-46-5.

What is the molecular formula of 2-chloro-4-(1-methyl-1H-imidazole-2-carbonyl)quinoline?

The molecular formula of 2-chloro-4-(1-methyl-1H-imidazole-2-carbonyl)quinoline is C14H10ClN3O.

What is the molecular weight of 2-chloro-4-(1-methyl-1H-imidazole-2-carbonyl)quinoline?

The molecular weight of 2-chloro-4-(1-methyl-1H-imidazole-2-carbonyl)quinoline is 271.05 g/mol.

Where can I buy 2-chloro-4-(1-methyl-1H-imidazole-2-carbonyl)quinoline?

You can request a quote for 2-chloro-4-(1-methyl-1H-imidazole-2-carbonyl)quinoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 2-chloro-4-(1-methyl-1H-imidazole-2-carbonyl)quinoline?

Yes, KEHONG BIO provides custom synthesis services for 2-chloro-4-(1-methyl-1H-imidazole-2-carbonyl)quinoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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